2. Gene
  3. Tpmt - thiopurine methyltransferase Gene

Tpmt - thiopurine methyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 22017 | 基因类型: protein coding

关于 Tpmt

功能概要

Enables thiopurine S-methyltransferase activity. Predicted to be involved in xenobiotic metabolic process. Predicted to act upstream of or within methylation. Predicted to be located in cytoplasm. Is expressed in metanephros. Used to study thiopurine S-methyltransferase deficiency. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Tpmt 基因产物(1)

mRNA Protein Name
NM_016785.2 NP_058065.2 thiopurine S-methyltransferase
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables thiopurine S-methyltransferase activity IDA
IDA: 通过直接分析推断
9539138 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thiopurine S-methyltransferase

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14940 TPMT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-134062 7-Methyl-6-mercaptopurine / 否
HY-RS18794 Tpmt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25283 Tpmt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpmt NCBI NCBI:7172
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