2. Gene
  3. Ube2a - ubiquitin-conjugating enzyme E2A Gene

Ube2a - ubiquitin-conjugating enzyme E2A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HR6A; HHR6A; Mhr6a

基因 ID: 22209 | 基因类型: protein coding

关于 Ube2a

功能概要

Enables ubiquitin conjugating enzyme activity and ubiquitin protein Ligase binding activity. Acts upstream of or within blastocyst hatching; maternal process involved in female pregnancy; and protein ubiquitination. Located in XY body and chromatin. Is expressed in several structures, including alimentary system; brain; female reproductive system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Orthologous to human UBE2A (ubiquitin conjugating enzyme E2 A). [provided by Alliance of Genome Resources, Apr 2022]

Ube2a 基因产物(2)

mRNA Protein Name
NM_001313696.1 NP_001300625.1 ubiquitin-conjugating enzyme E2 A isoform 2
NM_019668.4 NP_062642.1 ubiquitin-conjugating enzyme E2 A isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12509447 MGI
enables ubiquitin conjugating enzyme activity IGI
IGI: 通过遗传相互作用推断
17462990 MGI
enables ubiquitin protein ligase binding IDA
IDA: 通过直接分析推断
17462990 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
27869233 MGI
acts upstream of or within in utero embryonic development IGI
IGI: 通过遗传相互作用推断
15169909 MGI
NOT acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
15169909 MGI
acts upstream of or within maternal process involved in female pregnancy IMP
IMP: 通过突变表型推断
15169909 MGI
involved in positive regulation of mitophagy IMP
IMP: 通过突变表型推断
23685073 MGI
acts upstream of or within protein ubiquitination IDA
IDA: 通过直接分析推断
25023518 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in XY body IDA
IDA: 通过直接分析推断
15383616 MGI
located in chromatin IDA
IDA: 通过直接分析推断
15383616 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin-conjugating enzyme E2 A

E2 ubiquitin-conjugating enzyme A

RAD6 homolog A

ubiquitin carrier protein A

ubiquitin-conjugating enzyme E2A (RAD6 homolog)

ubiquitin-conjugating enzyme HR6A

ubiquitin-protein ligase A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15336 UBE2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18553 Ube2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25035 Ube2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ube2a NCBI NCBI:7319
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