1. Gene
  2. Ung - uracil DNA glycosylase Gene

Ung - uracil DNA glycosylase Gene

种属: Mus musculus

同用名: UNG1; UNG2

基因 ID: 22256 | 基因类型: protein coding

关于 Ung

功能概要

Enables uracil DNA N-glycosylase activity. Acts upstream of or within isotype switching and somatic hypermutation of immunoglobulin genes. Located in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and olfactory epithelium. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Orthologous to human UNG (uracil DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Ung 基因产物(2)

mRNA Protein Name
NM_001040691.1 NP_001035781.1 uracil-DNA glycosylase isoform a
NM_011677.2 NP_035807.2 uracil-DNA glycosylase isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables uracil DNA N-glycosylase activity IDA
IDA: 通过直接分析推断
10871356 MGI
enables uracil DNA N-glycosylase activity IMP
IMP: 通过突变表型推断
15494304 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
10871356 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10871356 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

uracil-DNA glycosylase

UDG

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ung NCBI NCBI:7374
Macaca mulatta Ung NCBI NCBI:706816