2. Gene
  3. ALDH9A1 - aldehyde dehydrogenase 9 family member A1 Gene

ALDH9A1 - aldehyde dehydrogenase 9 family member A1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：醛脱氢酶 9 家族成员 A1

种属: Homo sapiens

同用名: E3; ALDH4; ALDH7; ALDH9; TMABADH; TMABA-DH; TMABALDH

基因 ID: 223 | 基因类型: protein coding

关于 ALDH9A1

Cytogenetic location: 1q24.1 Genomic coordinates (GRCh38): 1:165,662,216-165,698,562 (from NCBI)

This gene has 5 transcripts (splice variants), 219 orthologues and 17 paralogues. Ubiquitous expression in fat (RPKM 90.6), thyroid (RPKM 83.5) and 25 other tissues.

功能概要

这种蛋白质属于蛋白质的醛脱氢酶家族。它对γ-氨基丁醛和其他氨基醛具有高氧化活性。该酶催化 γ-氨基丁醛脱氢为 γ-氨基丁酸 (GABA) 。该同功酶是相同的 54-kD 亚基的四聚体。[RefSeq 提供，2008 年 7 月]

This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and Other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]

ALDH9A1 基因产物(2)

mRNA Protein Name
NM_000696.4 NP_000687.3 4-trimethylaminobutyraldehyde dehydrogenase isoform 1
NM_001365774.2 NP_001352703.1 4-trimethylaminobutyraldehyde dehydrogenase isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 4-trimethylammoniobutyraldehyde dehydrogenase activity EXP
EXP: 通过实验结果推断
2925663 GOA
enables 4-trimethylammoniobutyraldehyde dehydrogenase activity IDA
IDA: 通过直接分析推断
30914451 GOA
enables aldehyde dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
1799975 GOA
enables aminobutyraldehyde dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
1799975 GOA
enables formaldehyde dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
2071588 GOA
enables small molecule binding EXP
EXP: 通过实验结果推断
30914451 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular aldehyde metabolic process IDA
IDA: 通过直接分析推断
8645224 GOA
involved in protein homotetramerization IDA
IDA: 通过直接分析推断
30914451 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
1799975 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ALDH9A1 蛋白结构

Aldedh

Aldedh: Aldehyde dehydrogenase family (51 - 507)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 518 a.a.
蛋白主名 其他名称

4-trimethylaminobutyraldehyde dehydrogenase

R-aminobutyraldehyde dehydrogenase

关联疾病

疾病名称 别名
Alcohol Dependence

Alcoholism

Alcohol Dependence, Susceptibility To

Alcohol Dependence, Protection Against

Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

Alcoholism, Susceptibility To

Alcoholic Intoxication, Chronic

Pharyngeal Neoplasms

Chronic Alcoholism

Dipsomania

Alcohol Addiction

Ethanol Dependence

Chronic Ethanolism

Chronic Alcoholic Disease Nos

Alcoholic Disease Nos

Alcoholic
Alcohol Use Disorder

Alcohol Abuse

Alcoholism

Ethanol Abuse

Alcohol Addiction

Alcohol Dependence

Alcoholic Intoxication, Chronic

Alcohol-Related Disorders
Gamma-Amino Butyric Acid Metabolism Disorder

Disorder Of Gamma-Aminobutyric Acid Metabolism

Disorder Of Gaba Metabolism

Disorders Of Gaba - [Gamma Aminobutyric Acid] Metabolism
Succinic Semialdehyde Dehydrogenase Deficiency

4-Hydroxybutyric Aciduria

Ssadh Deficiency

Gamma-Hydroxybutyric Aciduria

Gaba Metabolic Defect

SSADHD

Ssadh

Succinate-Semialdehyde Dehydrogenase Deficiency

Gamma-Hydroxybutyricaciduria

4-Hydroxybutyricaciduria

Gamma-Hydroxybutyric Acidemia

Succinate Semialdehyde Dehydrogenase Deficiency
Hyperprolinemia

Proline Oxidase Deficiency

Hyperprolinemia Type 1

Proline Hydrogenase Deficiency

Prolinemia

Pyrroline Carboxylate Dehydrogenase Deficiency

Pyrroline-5-Carboxylate Dehydrogenase Deficiency

Proline Dehydrogenase Deficiency

Hyperprolinemia Type 2
Alcoholic Hepatitis

Acute Alcoholic Hepatitis

Acute Alcoholic Liver Disease

Hepatitis, Alcoholic

Hepatitis Alcoholic

Ah - [Alcoholic Hepatitis]

Ethanol Hepatitis
Alcoholic Liver Cirrhosis

Alcoholic Cirrhosis

Portal Cirrhosis

Alcoholic Cirrhosis Of Liver

Liver Cirrhosis, Alcoholic

Laennec'S Cirrhosis

Laennec'S Cirrhosis, Alcoholic

Alcohol Cirrhosis

Alcoholic Laennec Cirrhosis

Alcoholic Cirrhosis Nos

Etoh Cirrhosis

Alcohol Hepatic Cirrhosis

Alcohol Liver Cirrhosis

Laennec Cirrhosis
Pleurisy
Sjogren-Larsson Syndrome

Sjögren-Larsson Syndrome

SLS

Faldh Deficiency

Fatty Aldehyde Dehydrogenase Deficiency

Fatty Acid Alcohol Oxidoreductase Deficiency

Ichthyosis, Spastic Neurologic Disorder, And Oligophrenia

Sjogren Larsson Syndrome

Fatty Alcohol:Nad+ Oxidoreductase Deficiency

Sjogren-Larsson'S Syndrome

Fadh Deficiency

Fao Deficiency

Congenital Icthyosis Mental Retardation Spasticity Syndrome

Ichthyosis Oligophrenia Syndrome

Sjoegren-Larsson Syndrome
Cataract

Cataracts

Cat - [Cataract]

Cataract Form

Lens Opacity

Lens Opacities
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00582 ALDH9A1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ALDH9A1 VGNC VGNC:37791
Rattus norvegicus ALDH9A1 RGD RGD:68409
Felis catus ALDH9A1 VGNC VGNC:97346
Mus musculus ALDH9A1 MGD MGI:1861622
Bos taurus ALDH9A1 VGNC VGNC:25820
Macaca mulatta ALDH9A1 VGNC VGNC:99842
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