2. Gene
  3. Vamp1 - vesicle-associated membrane protein 1 Gene

Vamp1 - vesicle-associated membrane protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: lew; Syb1; Syb-1; VAMP-1

基因 ID: 22317 | 基因类型: protein coding

关于 Vamp1

功能概要

Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in SNARE complex assembly; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle priming. Located in cell surface. Is active in glutamatergic synapse and neuromuscular junction. Is expressed in brain; cerebellum molecular layer; and ventral tegmental area. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Orthologous to human VAMP1 (vesicle associated membrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Vamp1 基因产物(2)

mRNA Protein Name
NM_001080557.1 NP_001074026.1 vesicle-associated membrane protein 1 isoform b
NM_009496.3 NP_033522.1 vesicle-associated membrane protein 1 isoform a
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SNARE complex assembly IDA
IDA: 通过直接分析推断
21151919 MGI
involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane IDA
IDA: 通过直接分析推断
21282288 MGI
involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane IMP
IMP: 通过突变表型推断
21282288 MGI
involved in synaptic vesicle priming IDA
IDA: 通过直接分析推断
24944211 MGI
involved in synaptic vesicle priming IMP
IMP: 通过突变表型推断
24944211 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
21151919 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24944211 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
24944211 MGI
is active in neuromuscular junction IDA
IDA: 通过直接分析推断
21282288 MGI
is active in neuromuscular junction IMP
IMP: 通过突变表型推断
21282288 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vesicle-associated membrane protein 1

synaptobrevin-1

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10809 VAMP Inhibitor / 否
HY-RS15593 VAMP1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vamp1 NCBI NCBI:6843
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