1. Gene
  2. Vrk1 - vaccinia related kinase 1 Gene

Vrk1 - vaccinia related kinase 1 Gene

种属: Mus musculus

同用名: 51PK

基因 ID: 22367 | 基因类型: protein coding

关于 Vrk1

功能概要

Enables protein serine/threonine kinase activity. Acts upstream of or within protein autophosphorylation. Located in nucleus. Is expressed in several structures, including dorsal mesogastrium; hemolymphoid system; liver; metanephros; and yolk sac. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Vrk1 基因产物(6)

mRNA Protein Name
NM_001029843.2 NP_001025014.1 serine/threonine-protein kinase VRK1 isoform b
NM_001029844.2 NP_001025015.1 serine/threonine-protein kinase VRK1 isoform c
NM_001364365.1 NP_001351294.1 serine/threonine-protein kinase VRK1 isoform c
NM_001364367.1 NP_001351296.1 serine/threonine-protein kinase VRK1 isoform a
NM_001364368.1 NP_001351297.1 serine/threonine-protein kinase VRK1 isoform d
NM_011705.4 NP_035835.1 serine/threonine-protein kinase VRK1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
14645249 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
14645249 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
14645249 MGI
involved in regulation of neuron migration IMP
IMP: 通过突变表型推断
25609612 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
14645249 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase VRK1

serine/threonine-protein kinase 51PK

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vrk1 NCBI NCBI:7443