2. Gene
  3. Traf7 - TNF receptor-associated factor 7 Gene

Traf7 - TNF receptor-associated factor 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RFWD1

基因 ID: 224619 | 基因类型: protein coding

关于 Traf7

功能概要

Predicted to enable ubiquitin-protein transferase activity. Acts upstream of or within several processes, including cellular response to interleukin-6; negative regulation of transcription by RNA polymerase II; and positive regulation of protein sumoylation. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Is expressed in genitourinary system and pancreas epithelium. Orthologous to human TRAF7 (TNF Receptor associated factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Traf7 基因产物(3)

mRNA Protein Name
NM_001172113.1 NP_001165584.1 E3 ubiquitin-protein ligase TRAF7 isoform 1
NM_001172114.1 NP_001165585.1 E3 ubiquitin-protein ligase TRAF7 isoform 2
NM_153792.2 NP_722487.2 E3 ubiquitin-protein ligase TRAF7 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16162816 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to interleukin-6 IDA
IDA: 通过直接分析推断
16162816 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16162816 MGI
acts upstream of or within positive regulation of protein sumoylation IDA
IDA: 通过直接分析推断
16162816 MGI
acts upstream of or within regulation of protein localization IDA
IDA: 通过直接分析推断
16162816 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
16162816 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16162816 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
16162816 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase TRAF7

RING-type E3 ubiquitin transferase TRAF7

ring finger and WD repeat domain 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14976 TRAF7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20502 Traf7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27010 Traf7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Traf7 NCBI NCBI:84231
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