2. Gene
  3. Ndufs1 - NADH:ubiquinone oxidoreductase core subunit S1 Gene

Ndufs1 - NADH:ubiquinone oxidoreductase core subunit S1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 5830412M15Rik; 9930026A05Rik

基因 ID: 227197 | 基因类型: protein coding

关于 Ndufs1

功能概要

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in inherited metabolic disorder; mitochondrial complex I deficiency; and nuclear type mitochondrial complex I deficiency 5. Orthologous to human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1). [provided by Alliance of Genome Resources, Apr 2022]

Ndufs1 基因产物(4)

mRNA Protein Name
NM_001160038.1 NP_001153510.1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor
NM_001160039.1 NP_001153511.1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor
NM_001160040.1 NP_001153512.1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor
NM_145518.2 NP_663493.2 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NADH dehydrogenase (ubiquinone) activity IMP
IMP: 通过突变表型推断
27799543 MGI
enables electron transfer activity IMP
IMP: 通过突变表型推断
27799543 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
32072193 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial respiratory chain complex I assembly IMP
IMP: 通过突变表型推断
27799543 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
32072193 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

CI-75kD

NADH dehydrogenase (ubiquinone) Fe-S protein 1

complex I-75kD

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09157 NDUFS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21162 Ndufs1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27678 Ndufs1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndufs1 NCBI NCBI:4719
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