1. Gene
  2. Aldob - aldolase B, fructose-bisphosphate Gene

Aldob - aldolase B, fructose-bisphosphate Gene

种属: Mus musculus

同用名: Aldo2; Aldo-2

基因 ID: 230163 | 基因类型: protein coding

关于 Aldob

功能概要

This gene encodes a subunit of the homotetrameric enzyme aldolase B, an isozyme of the class I fructose 1,6-bisphosphate aldolase enzyme. This enzyme catalyzes the conversion of fructose 1,6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Homozygous knockout mice for this gene exhibit liver damage and death following fructose ingestion. A pseudogene of this gene has been identified in the genome. [provided by RefSeq, Aug 2015]

Aldob 基因产物(1)

mRNA Protein Name
NM_144903.3 NP_659152.1 fructose-bisphosphate aldolase B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fructose-1-phosphate aldolase activity IMP
IMP: 通过突变表型推断
25637246 MGI
enables fructose-bisphosphate aldolase activity IDA
IDA: 通过直接分析推断
604178 MGI
enables fructose-bisphosphate aldolase activity IMP
IMP: 通过突变表型推断
25637246 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fructose catabolic process IDA
IDA: 通过直接分析推断
4343087 MGI
involved in fructose catabolic process IMP
IMP: 通过突变表型推断
29533924 MGI
involved in fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate IMP
IMP: 通过突变表型推断
29533924 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
32733884 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fructose-bisphosphate aldolase B

liver-type aldolase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aldob NCBI NCBI:229