2. Gene
  3. Kmt2c - lysine (K)-specific methyltransferase 2C Gene

Kmt2c - lysine (K)-specific methyltransferase 2C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HALR; Mll3; E330008K23Rik

基因 ID: 231051 | 基因类型: protein coding

关于 Kmt2c

功能概要

Predicted to enable histone binding activity; Histone Methyltransferase activity (H3-K4 specific); and transcription coactivator activity. Involved in histone methylation. Acts upstream of or within several processes, including eyelid development in camera-type eye; positive regulation of fibroblast proliferation; and single fertilization. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. Is expressed in several structures, including eye; genitourinary system; limb; nervous system; and neural ectoderm. Human ortholog(s) of this gene implicated in Klatskin's tumor; Kleefstra syndrome 2; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human KMT2C (lysine methyltransferase 2C). [provided by Alliance of Genome Resources, Apr 2022]

Kmt2c 基因产物(2)

mRNA Protein Name
NM_001081383.2 NP_001074852.1 histone-lysine N-methyltransferase 2C
NM_001081383.2 NP_001074852.1 histone-lysine N-methyltransferase 2C
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K4 methyltransferase activity IDA
IDA: 通过直接分析推断
18172164 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17021013 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within eyelid development in camera-type eye IMP
IMP: 通过突变表型推断
17021013 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
17021013 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: 通过突变表型推断
17021013 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
17021013 MGI
acts upstream of or within single fertilization IMP
IMP: 通过突变表型推断
17021013 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase 2C

histone-lysine N-methyltransferase MLL3

myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07403 KMT2C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20048 Kmt2c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26552 Kmt2c Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kmt2c NCBI NCBI:58508
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z