1. Gene
  2. Tmem119 - transmembrane protein 119 Gene

Tmem119 - transmembrane protein 119 Gene

种属: Mus musculus

同用名: obif

基因 ID: 231633 | 基因类型: protein coding

关于 Tmem119

功能概要

Involved in several processes, including endochondral ossification; negative regulation of bone resorption; and positive regulation of macromolecule metabolic process. Acts upstream of or within osteoblast differentiation. Located in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and skeleton. Orthologous to human TMEM119 (transmembrane protein 119). [provided by Alliance of Genome Resources, Apr 2022]

Tmem119 基因产物(1)

mRNA Protein Name
NM_146162.3 NP_666274.1 transmembrane protein 119 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21239498 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endochondral ossification IMP
IMP: 通过突变表型推断
22416756 MGI
involved in negative regulation of bone resorption IMP
IMP: 通过突变表型推断
22416756 MGI
involved in negative regulation of myotube differentiation IDA
IDA: 通过直接分析推断
22579779 MGI
acts upstream of or within osteoblast differentiation IDA
IDA: 通过直接分析推断
21239498 MGI
acts upstream of or within osteoblast differentiation IMP
IMP: 通过突变表型推断
21239498 MGI
involved in positive regulation of bone development IMP
IMP: 通过突变表型推断
26207632 MGI
involved in positive regulation of bone mineralization IMP
IMP: 通过突变表型推断
20025746 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
22579779 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
22416756 MGI
involved in positive regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
22579779 MGI
involved in positive regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
20025746 MGI
involved in positive regulation of osteoblast proliferation IDA
IDA: 通过直接分析推断
20025746 MGI
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
22579779 MGI
involved in spermatid differentiation IMP
IMP: 通过突变表型推断
26207632 MGI
involved in spermatogenesis IMP
IMP: 通过突变表型推断
26207632 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
21239498 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
20025746 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transmembrane protein 119

osteoblast induction factor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tmem119 NCBI NCBI:338773