1. Gene
  2. Hmces - 5-hydroxymethylcytosine (hmC) binding, ES cell specific Gene

Hmces - 5-hydroxymethylcytosine (hmC) binding, ES cell specific Gene

种属: Mus musculus

同用名: Srap1; 8430410A17Rik

基因 ID: 232210 | 基因类型: protein coding

关于 Hmces

功能概要

Enables single-stranded DNA binding activity. Involved in double-strand break repair via alternative nonhomologous end joining and positive regulation of isotype switching. Predicted to be located in replication fork. Is expressed in several structures, including adipose tissue; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human HMCES (5-hydroxymethylcytosine binding, ES cell specific). [provided by Alliance of Genome Resources, Apr 2022]

Hmces 基因产物(1)

mRNA Protein Name
NM_173737.2 NP_776098.1 abasic site processing protein HMCES
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
31806351 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in double-strand break repair via alternative nonhomologous end joining IDA
IDA: 通过直接分析推断
31806351 MGI
involved in positive regulation of isotype switching IDA
IDA: 通过直接分析推断
31806351 MGI
involved in somatic hypermutation of immunoglobulin genes IDA
IDA: 通过直接分析推断
35450882 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

abasic site processing protein HMCES

ES cell-specific 5hmC-binding protein

SRAP domain-containing protein 1

UPF0361 protein C3orf37 homolog

embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein

peptidase HMCES

putative endonuclease HMCES

putative peptidase SRAPD1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hmces NCBI NCBI:56941