1. Gene
  2. P2ry6 - pyrimidinergic receptor P2Y, G-protein coupled, 6 Gene

P2ry6 - pyrimidinergic receptor P2Y, G-protein coupled, 6 Gene

中文名称:嘧啶能受体 P2 Y,G 蛋白偶联,6

种属: Mus musculus

同用名: P2Y6; 2010204J23Rik

基因 ID: 233571 | 基因类型: protein coding

关于 P2ry6

Chromosome 7: 100,586,837-100,623,856 reverse strand.GRCm39:CM001000.3

This gene has 3 transcripts (splice variants), 183 orthologues, 13 paralogues and is associated with 3 phenotypes. Broad expression in colon adult (RPKM 37.), lung adult (RPKM 23.5) and 16 other tissues.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联的 UDP 受体活性。作用于有机环状化合物的细胞反应上游或细胞反应内;细胞对前列腺素 E 刺激的反应;和跨上皮氯化物转运。预测位于顶端质膜和基底外侧质膜。在 dermomyotome 和肌肉组织中表达。与人 P2RY6(嘧啶能受体 P2Y6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables G protein-coupled UDP receptor activity. Acts upstream of or within cellular response to organic cyclic compound; cellular response to prostaglandin E stimulus; and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Is expressed in dermomyotome and musculature. Orthologous to human P2RY6 (pyrimidinergic receptor P2Y6). [provided by Alliance of Genome Resources, Apr 2022]

P2ry6 基因产物(1)

mRNA Protein Name
NM_183168.2 NP_898991.1 P2Y purinoceptor 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled UDP receptor activity IDA
IDA: 通过直接分析推断
11259526 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: 通过直接分析推断
23479225 MGI
acts upstream of or within cellular response to prostaglandin E stimulus IDA
IDA: 通过直接分析推断
23479225 MGI
acts upstream of or within transepithelial chloride transport IDA
IDA: 通过直接分析推断
11259526 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

P2ry6 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (26 - 311)

7tm_GPCRs

7tm_GPCRs: cd14964 (28 - 52)

7tm_GPCRs

7tm_GPCRs: cd14964 (61 - 82)

7tm_GPCRs

7tm_GPCRs: cd14964 (99 - 121)

7tm_GPCRs

7tm_GPCRs: cd14964 (145 - 161)

7tm_GPCRs

7tm_GPCRs: cd14964 (189 - 212)

7tm_GPCRs

7tm_GPCRs: cd14964 (237 - 259)

7tm_GPCRs

7tm_GPCRs: cd14964 (279 - 304)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
蛋白主名 其他名称

P2Y purinoceptor 6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P2ry6 NCBI NCBI:5031