2. Gene
  3. Setd1a - SET domain containing 1A Gene

Setd1a - SET domain containing 1A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: KMT2F; mNSC1; Nsccn1; mKIAA0339

基因 ID: 233904 | 基因类型: protein coding

关于 Setd1a

功能概要

Predicted to enable beta-catenin binding activity and Histone Methyltransferase activity (H3-K4 specific). Involved in several processes, including histone H3-K4 methylation; regulation of chromatin organization; and regulation of erythrocyte differentiation. Acts upstream of or within positive regulation of neural precursor cell proliferation; positive regulation of stem cell proliferation; and stem cell population maintenance. Located in euchromatin and nucleus. Is expressed in several structures, including early conceptus; integumental system; liver; nervous system; and oocyte. Orthologous to human SETD1A (SET domain containing 1A, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Setd1a 基因产物(1)

mRNA Protein Name
NM_178029.3 NP_821172.2 histone-lysine N-methyltransferase SETD1A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K4 methyltransferase activity IMP
IMP: 通过突变表型推断
24550110 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
29490266 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in brain development IMP
IMP: 通过突变表型推断
31197650 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
27141965 MGI
acts upstream of or within positive regulation of neural precursor cell proliferation IMP
IMP: 通过突变表型推断
24550110 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: 通过突变表型推断
24550110 MGI
involved in regulation of chromatin organization IDA
IDA: 通过直接分析推断
27141965 MGI
involved in regulation of erythrocyte differentiation IMP
IMP: 通过突变表型推断
27141965 MGI
acts upstream of or within stem cell population maintenance IMP
IMP: 通过突变表型推断
24550110 MGI
acts upstream of stem cell proliferation IMP
IMP: 通过突变表型推断
24550110 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in euchromatin IDA
IDA: 通过直接分析推断
22723415 MGI
located in nucleus IDA
IDA: 通过直接分析推断
24550110 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase SETD1A

SET domain-containing protein 1A

non-selective cation channel 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12740 SETD1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19526 Setd1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26021 Setd1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Setd1a NCBI NCBI:9739
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