1. Gene
  2. SLC16A8 - solute carrier family 16 member 8 Gene

SLC16A8 - solute carrier family 16 member 8 Gene

中文名称:溶质载体家族 16 成员 8

种属: Homo sapiens

同用名: MCT3; REMP

基因 ID: 23539 | 基因类型: protein coding

关于 SLC16A8

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,078,137-38,084,184 (from NCBI)

This gene has 4 transcripts (splice variants), 170 orthologues and 13 paralogues. Broad expression in prostate (RPKM 2.1), testis (RPKM 0.9) and 20 other tissues.

功能概要

SLC16A8 是介导乳酸跨细胞膜转运的质子偶联单羧酸转运蛋白家族的成员 (Yoon 等人,1999 [PubMed 10493836]) 。[OMIM 提供,2010 年 4 月]

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010]

SLC16A8 基因产物(2)

mRNA Protein Name
NM_001394131.1 NP_001381060.1 monocarboxylate transporter 3 isoform 2
NM_013356.3 NP_037488.2 monocarboxylate transporter 3 isoform 1

SLC16A8 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (26 - 328)

  • 0
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  • 200
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  • 400
  • 504 a.a.
蛋白主名 其他名称

monocarboxylate transporter 3

MCT 3

关联疾病

疾病名称 别名
Macular Degeneration, Age-Related, 1

Macular Degeneration

Age-Related Macular Degeneration

Macular Degeneration, Age-Related

Age Related Macular Degeneration

Age Related Macular Degeneration 1

ARMD1

Senile Macular Degeneration

Maculopathy, Age-Related, 1

Macular Degeneration, Age-Related, Reduced Risk Of

Age Related Maculopathy 1

Age Related Maculopathies

Age Related Maculopathy

Senile Macular Retinal Degeneration

Macular Degeneration Of Retina

Age-Related Maculopathy

Amd

Armd

Age-Related Maculopathy, Susceptibility To

Maculopathy Age-Related

Macular Degeneration, Age-Related, 1, Susceptibility To

Maculopathy, Age-Related

Macular Degeneration, Age-Related, Type 1

Macular Degeneration, Age-Related, 2

Fundus Dystrophy

Retinal Dystrophy

Retinal Dystrophies

Dystrophy, Retinal

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus SLC16A8 VGNC VGNC:65215
Macaca mulatta SLC16A8 VGNC VGNC:108037
Canis familiaris SLC16A8 VGNC VGNC:46246
Rattus norvegicus SLC16A8 RGD RGD:69282
Mus musculus SLC16A8 MGD MGI:1929519
Bos taurus SLC16A8 VGNC VGNC:34694