2. Gene
  3. Ets1 - E26 avian leukemia oncogene 1, 5' domain Gene

Ets1 - E26 avian leukemia oncogene 1, 5' domain Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: vs; p54; Tpl1; Ets-1; D230050P06

基因 ID: 23871 | 基因类型: protein coding

关于 Ets1

功能概要

Enables DNA-binding transcription factor activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of inflammatory response. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Ets1 基因产物(6)

mRNA Protein Name
NM_001038642.2 NP_001033731.1 protein C-ets-1 isoform 2
NM_001372534.1 NP_001359463.1 protein C-ets-1 isoform 3
NM_001372535.1 NP_001359464.1 protein C-ets-1 isoform 4
NM_001372536.1 NP_001359465.1 protein C-ets-1 isoform 5
NM_001372537.1 NP_001359466.1 protein C-ets-1 isoform 6
NM_011808.3 NP_035938.2 protein C-ets-1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
7774816 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12119294 MGI
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
9199349 MGI
enables nucleic acid binding EXP
EXP: 通过实验结果推断
15994560 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7774816 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
1409581 MGI
enables sequence-specific double-stranded DNA binding IMP
IMP: 通过突变表型推断
15994560 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
22294049 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12464608 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12119294 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
12464608 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15541767 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12119294 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
12464608 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein C-ets-1

avian erythroblastosis virus E26 oncogene 1

tumor progression locus 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04562 ETS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16879 Ets1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23321 Ets1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ets1 NCBI NCBI:2113
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