2. Gene
  3. Impdh1 - inosine monophosphate dehydrogenase 1 Gene

Impdh1 - inosine monophosphate dehydrogenase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IMPDH-I; B930086D20Rik

基因 ID: 23917 | 基因类型: protein coding

关于 Impdh1

功能概要

Enables IMP dehydrogenase activity. Involved in 'de novo' XMP biosynthetic process and GMP biosynthetic process. Acts upstream of or within lymphocyte proliferation and purine nucleotide biosynthetic process. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Is expressed in central nervous system and retina outer nuclear layer. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Impdh1 基因产物(3)

mRNA Protein Name
NM_001302933.1 NP_001289862.1 inosine-5'-monophosphate dehydrogenase 1 isoform 1
NM_001302934.1 NP_001289863.1 inosine-5'-monophosphate dehydrogenase 1 isoform 2
NM_011829.3 NP_035959.2 inosine-5'-monophosphate dehydrogenase 1 isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables IMP dehydrogenase activity IDA
IDA: 通过直接分析推断
12944494 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 'de novo' XMP biosynthetic process IMP
IMP: 通过突变表型推断
12944494 MGI
involved in GMP biosynthetic process IMP
IMP: 通过突变表型推断
12944494 MGI
acts upstream of or within lymphocyte proliferation IMP
IMP: 通过突变表型推断
12944494 MGI
acts upstream of or within purine nucleotide biosynthetic process IMP
IMP: 通过突变表型推断
12944494 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

inosine-5'-monophosphate dehydrogenase 1

IMP dehydrogenase 1

IMPD 1

IMPDH 1

inosine 5'-phosphate dehydrogenase 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-169296 IMPDH2-IN-4 / 否
HY-RS06798 IMPDH1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-164434 Xanthosine-5'-monophosphate / 否
HY-RS17781 Impdh1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24248 Impdh1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Impdh1 NCBI NCBI:3614
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