1. Gene
  2. Tenm4 - teneurin transmembrane protein 4 Gene

Tenm4 - teneurin transmembrane protein 4 Gene

种属: Mus musculus

同用名: Doc4; ELM2; Odz4; l7Rn3; Ten-m4; l(7)-3Rn; mKIAA1302

基因 ID: 23966 | 基因类型: protein coding

关于 Tenm4

功能概要

Enables protein homodimerization activity. Involved in central nervous system myelin formation; positive regulation of gastrulation; and regulation of nervous system development. Acts upstream of or within cardiac cell fate specification; cardiac muscle cell proliferation; and gastrulation with mouth forming second. Located in cytoplasm; neuron projection; and nucleus. Is integral component of plasma membrane. Is expressed in several structures, including branchial arch; central nervous system; forelimb bud; future brain; and somite. Human ortholog(s) of this gene implicated in essential tremor 5. Orthologous to human TENM4 (teneurin transmembrane protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Tenm4 基因产物(3)

mRNA Protein Name
NM_001310760.1 NP_001297689.1 teneurin-4 isoform 1
NM_001310762.1 NP_001297691.1 teneurin-4 isoform 3
NM_011858.4 NP_035988.2 teneurin-4 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12000766 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
12000766 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac cell fate specification IMP
IMP: 通过突变表型推断
17350578 MGI
acts upstream of or within cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
17350578 MGI
involved in central nervous system myelin formation IMP
IMP: 通过突变表型推断
22915103 MGI
acts upstream of or within gastrulation with mouth forming second IMP
IMP: 通过突变表型推断
15489520 MGI
involved in positive regulation of gastrulation IMP
IMP: 通过突变表型推断
15489520 MGI
involved in positive regulation of myelination IMP
IMP: 通过突变表型推断
22915103 MGI
involved in positive regulation of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
22915103 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
35484136 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22915103 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
35484136 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
22915103 MGI
located in nucleus IDA
IDA: 通过直接分析推断
22915103 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9649432 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

teneurin-4

downstream of CHOP4

odd Oz/ten-m homolog 4

protein Odd Oz/ten-m homolog 4

ten-4

tenascin-M4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tenm4 NCBI NCBI:26011