1. Gene
  2. Sulf1 - sulfatase 1 Gene

Sulf1 - sulfatase 1 Gene

种属: Mus musculus

同用名: MSulf-1; mKIAA1077

基因 ID: 240725 | 基因类型: protein coding

关于 Sulf1

功能概要

Enables N-acetylglucosamine-6-sulfatase activity. Involved in several processes, including esophagus smooth muscle contraction; glomerular filtration; and skeletal system development. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; limb; lower urogenital tract; and sensory organ. Orthologous to human SULF1 (sulfatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sulf1 基因产物(3)

mRNA Protein Name
NM_001198565.2 NP_001185494.1 extracellular sulfatase Sulf-1 precursor
NM_001198566.2 NP_001185495.1 extracellular sulfatase Sulf-1 precursor
NM_172294.2 NP_758498.1 extracellular sulfatase Sulf-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N-acetylglucosamine-6-sulfatase activity IMP
IMP: 通过突变表型推断
18687675 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bone development IGI
IGI: 通过遗传相互作用推断
17593974 MGI
involved in cartilage development IMP
IMP: 通过突变表型推断
20479257 MGI
involved in chondrocyte development IMP
IMP: 通过突变表型推断
20479257 MGI
involved in embryonic skeletal system development IGI
IGI: 通过遗传相互作用推断
18213582 MGI
involved in esophagus smooth muscle contraction IGI
IGI: 通过遗传相互作用推断
17720696 MGI
involved in glial cell-derived neurotrophic factor receptor signaling pathway IDA
IDA: 通过直接分析推断
17720696 MGI
involved in glomerular basement membrane development IGI
IGI: 通过遗传相互作用推断
21719793 MGI
involved in glomerular filtration IGI
IGI: 通过遗传相互作用推断
21719793 MGI
involved in heparan sulfate proteoglycan metabolic process IMP
IMP: 通过突变表型推断
18687675 MGI
involved in innervation IGI
IGI: 通过遗传相互作用推断
17720696 MGI
involved in kidney development IGI
IGI: 通过遗传相互作用推断
17593974 MGI
involved in negative regulation of fibroblast growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
20410206 MGI
involved in negative regulation of fibroblast growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
17593974 MGI
involved in negative regulation of prostatic bud formation IDA
IDA: 通过直接分析推断
20410206 MGI
involved in positive regulation of vascular endothelial growth factor production IGI
IGI: 通过遗传相互作用推断
21719793 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
21719793 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

extracellular sulfatase Sulf-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sulf1 NCBI NCBI:23213