CLDN15 - claudin 15 Gene

中文名称：紧密连接蛋白 15

种属: Homo sapiens

关于 CLDN15

功能概要

该基因编码密蛋白家族的一个成员。 Claudins 是完整的膜蛋白和紧密连接链的组成部分。紧密连接链作为物理屏障，防止溶质和水自由通过上皮或内皮细胞片之间的细胞旁空间，并且在维持细胞极性和信号转导中也起着关键作用。已发现该基因编码相同蛋白质的可变剪接转录物变体。[RefSeq 提供，2010 年 6 月]

This gene encodes a member of the Claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]