1. Gene
  2. Adcyap1 - adenylate cyclase activating polypeptide 1 Gene

Adcyap1 - adenylate cyclase activating polypeptide 1 Gene

种属: Rattus norvegicus

同用名: Pacap

基因 ID: 24166 | 基因类型: protein coding

关于 Adcyap1

功能概要

Enables neuropeptide hormone activity; pituitary Adenylate Cyclase activating polypeptide activity; and pituitary adenylate cyclase-activating polypeptide receptor binding activity. Involved in several processes, including negative regulation of acute inflammatory response; positive regulation of cell communication; and regulation of GTPase activity. Located in extracellular space and terminal bouton. Used to study Parkinsonism and acute necrotizing pancreatitis. Biomarker of cystitis. Orthologous to human ADCYAP1 (Adenylate Cyclase activating polypeptide 1). [provided by Alliance of Genome Resources, Apr 2022]

Adcyap1 基因产物(1)

mRNA Protein Name
NM_016989.2 NP_058685.1 pituitary adenylate cyclase-activating polypeptide precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables neuropeptide hormone activity IDA
IDA: 通过直接分析推断
23800469 RGD
enables pituitary adenylate cyclase activating polypeptide activity IDA
IDA: 通过直接分析推断
9603988 RGD
enables pituitary adenylate cyclase-activating polypeptide receptor binding IDA
IDA: 通过直接分析推断
8238511 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
9603988 RGD
involved in behavioral fear response IDA
IDA: 通过直接分析推断
17641738 RGD
involved in cAMP-mediated signaling IMP
IMP: 通过突变表型推断
23800469 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
17884294 RGD
involved in histamine secretion IDA
IDA: 通过直接分析推断
17660849 RGD
involved in negative regulation of GTPase activity IDA
IDA: 通过直接分析推断
15870074 RGD
involved in negative regulation of acute inflammatory response to antigenic stimulus IDA
IDA: 通过直接分析推断
17698245 RGD
involved in negative regulation of acute inflammatory response to non-antigenic stimulus IDA
IDA: 通过直接分析推断
20229361 RGD
involved in negative regulation of glial cell proliferation IDA
IDA: 通过直接分析推断
15870074 RGD
involved in negative regulation of muscle cell apoptotic process IDA
IDA: 通过直接分析推断
16891268 RGD
involved in negative regulation of potassium ion transport IDA
IDA: 通过直接分析推断
17498241 RGD
involved in neuron projection development IDA
IDA: 通过直接分析推断
23800469 RGD
involved in neuropeptide signaling pathway IDA
IDA: 通过直接分析推断
23800469 RGD
involved in ovarian follicle development IDA
IDA: 通过直接分析推断
20138961 RGD
involved in pituitary gland development IEP
IEP: 通过表达模式推断
18160680 RGD
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
23800469 RGD
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
23800469 RGD
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: 通过直接分析推断
17901570 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
15968088 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
18198219 RGD
involved in positive regulation of growth hormone secretion IDA
IDA: 通过直接分析推断
18198219 RGD
involved in positive regulation of interleukin-6 production IDA
IDA: 通过直接分析推断
16888221 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
18541665 RGD
involved in positive regulation of neuron projection development IGI
IGI: 通过遗传相互作用推断
18541665 RGD
involved in positive regulation of protein kinase activity IDA
IDA: 通过直接分析推断
23800469 RGD
involved in positive regulation of somatostatin secretion IDA
IDA: 通过直接分析推断
17660849 RGD
involved in positive regulation of synaptic transmission, glutamatergic IDA
IDA: 通过直接分析推断
16483357 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
23800469 RGD
involved in regulation of oligodendrocyte progenitor proliferation IDA
IDA: 通过直接分析推断
16989910 RGD
involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
18727050 RGD
involved in regulation of protein localization IDA
IDA: 通过直接分析推断
9603988 RGD
involved in regulation of protein phosphorylation IGI
IGI: 通过遗传相互作用推断
18541665 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
16820725 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
16888191 RGD
involved in vasodilation IDA
IDA: 通过直接分析推断
19220306 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17698245 RGD
is active in neuronal dense core vesicle lumen IDA
IDA: 通过直接分析推断
9792613 RGD
located in terminal bouton IDA
IDA: 通过直接分析推断
9792613 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pituitary adenylate cyclase-activating polypeptide

adenylate cyclase activating polypeptide 1 (pituitary)

pituitary adenylate cyclase activating polypeptide 1

pituitary adenylate cyclase-activating polypeptide precursor (Pacap)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adcyap1 NCBI NCBI:116