1. Gene
  2. Adra2c - adrenoceptor alpha 2C Gene

Adra2c - adrenoceptor alpha 2C Gene

种属: Rattus norvegicus

基因 ID: 24175 | 基因类型: protein coding

关于 Adra2c

功能概要

Predicted to enable several functions, including alpha-2A Adrenergic Receptor binding activity; alpha2-adrenergic receptor activity; and protein dimerization activity. Involved in several processes, including negative regulation of uterine smooth muscle contraction; positive regulation of vasoconstriction; and regulation of sensory perception of pain. Located in axon terminus and neuronal cell body. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human ADRA2C (adrenoceptor alpha 2C). [provided by Alliance of Genome Resources, Apr 2022]

Adra2c 基因产物(1)

mRNA Protein Name
NM_138506.2 NP_612515.2 alpha-2C adrenergic receptor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female pregnancy IMP
IMP: 通过突变表型推断
19450576 RGD
involved in negative regulation of uterine smooth muscle contraction IMP
IMP: 通过突变表型推断
17664026 RGD
involved in positive regulation of vasoconstriction IMP
IMP: 通过突变表型推断
20862454 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15207357 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
12379250 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
9552127 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
9552127 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12379250 RGD
is active in postsynaptic density membrane EXP
EXP: 通过实验结果推断
9552127 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
9552127 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
9552127 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

alpha-2C adrenergic receptor

Adrenergic alpha2C- receptor class I

Adrenergic, alpha2C-, receptor class I

adrenergic receptor, alpha 2c

adrenergic, alpha-2C-, receptor

alpha-2 adrenergic receptor subtype C4

alpha-2C adrenoceptor

alpha-2C adrenoreceptor

alpha-2CAR

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adra2c NCBI NCBI:152