1. Gene
  2. Aldob - aldolase, fructose-bisphosphate B Gene

Aldob - aldolase, fructose-bisphosphate B Gene

种属: Rattus norvegicus

同用名: Aldo2; LIV10

基因 ID: 24190 | 基因类型: protein coding

关于 Aldob

功能概要

Enables fructose-bisphosphate aldolase activity and phosphatidylcholine binding activity. Involved in several processes, including cellular response to Insulin stimulus; response to copper ion; and response to fructose. Located in several cellular components, including endoplasmic reticulum membrane; lysosome; and perinuclear region of cytoplasm. Used to study type 2 diabetes mellitus. Biomarker of liver benign neoplasm; peritonitis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B). [provided by Alliance of Genome Resources, Apr 2022]

Aldob 基因产物(1)

mRNA Protein Name
NM_012496.2 NP_036628.2 fructose-bisphosphate aldolase B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fructose-bisphosphate aldolase activity IDA
IDA: 通过直接分析推断
9448062 RGD
enables phosphatidylcholine binding IPI
IPI: 通过物理相互作用推断
9448062 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
9473304 RGD
involved in liver development IEP
IEP: 通过表达模式推断
8641049 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
2984252 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
2984252 RGD
involved in response to carbohydrate IEP
IEP: 通过表达模式推断
6689021 RGD
involved in response to copper ion IEP
IEP: 通过表达模式推断
11044632 RGD
involved in response to fructose IEP
IEP: 通过表达模式推断
2984252 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
9473304 RGD
involved in response to interleukin-6 IEP
IEP: 通过表达模式推断
7625825 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
9020521 RGD
involved in response to peptide hormone IDA
IDA: 通过直接分析推断
10775441 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
9886486 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
12387752 RGD
involved in response to zinc ion IDA
IDA: 通过直接分析推断
12721403 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
10797566 RGD
located in rough endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
234468 RGD
located in smooth endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
234468 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fructose-bisphosphate aldolase B

Aldolase B, fructose-biphosphate

aldolase B, fructose-bisphosphate

liver-type aldolase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aldob NCBI NCBI:229