2. Gene
  3. Calca - calcitonin-related polypeptide alpha Gene

Calca - calcitonin-related polypeptide alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin

基因 ID: 24241 | 基因类型: protein coding

关于 Calca

功能概要

Predicted to enable Calcitonin receptor binding activity and identical protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; and vasodilation. Located in several cellular components, including axon; extracellular space; and neuronal cell body. Used to study acute necrotizing pancreatitis; ischemia; and stomach disease. Biomarker of prediabetes syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (Calcitonin related polypeptide alpha). [provided by Alliance of Genome Resources, Apr 2022]

Calca 基因产物(3)

mRNA Protein Name
NM_001033955.1 NP_001029127.1 calcitonin gene-related peptide 1 isoform Cgrp preproprotein
NM_001033956.1 NP_001029128.1 calcitonin gene-related peptide 1 isoform Cgrp preproprotein
NM_017338.2 NP_059034.1 calcitonin gene-related peptide 1 isoform Calca preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
21958434 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
21958434 RGD
involved in negative regulation of blood pressure IMP
IMP: 通过突变表型推断
11230364 RGD
involved in negative regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
11230364 RGD
involved in vasodilation IDA
IDA: 通过直接分析推断
12903912 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
11836000 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
11208722 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: 通过直接分析推断
9383204 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
11836000 RGD
is active in neuronal dense core vesicle IDA
IDA: 通过直接分析推断
9383204 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcitonin gene-related peptide 1

CGRP-I

alpha-type CGRP

calcitonin gene-related peptide I

calcitonin/calcitonin-related polypeptide, alpha

procalcitonin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01828 CALCA Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS18268 Calca Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS24746 Calca Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calca NCBI NCBI:796
Mus musculus Calca NCBI NCBI:12310
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