2. Gene
  3. Calm1 - calmodulin 1 Gene

Calm1 - calmodulin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CaMI; Calm; Cam1

基因 ID: 24242 | 基因类型: protein coding

关于 Calm1

功能概要

Enables several functions, including enzyme binding activity; transmembrane transporter binding activity; and type 3 metabotropic glutamate receptor binding activity. Involved in several processes, including activation of Adenylate Cyclase activity; regulation of calcium ion transmembrane transporter activity; and regulation of vesicle-mediated transport. Located in several cellular components, including growth cone; myelin sheath; and nucleus. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 4; long QT syndrome 14; and long QT syndrome 15. Orthologous to several human genes including CALM1 (Calmodulin 1). [provided by Alliance of Genome Resources, Apr 2022]

Calm1 基因产物(1)

mRNA Protein Name
NM_031969.3 NP_114175.1 calmodulin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
15628869 RGD
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
12032157 RGD
enables nitric-oxide synthase binding IDA
IDA: 通过直接分析推断
20529840 RGD
enables nitric-oxide synthase regulator activity IDA
IDA: 通过直接分析推断
20529840 RGD
enables phosphatidylinositol 3-kinase binding IPI
IPI: 通过物理相互作用推断
17492691 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11323678 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
21855531 RGD
enables transmembrane transporter binding IDA
IDA: 通过直接分析推断
15628869 RGD
enables type 3 metabotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
21855531 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in establishment of protein localization to membrane IMP
IMP: 通过突变表型推断
23792689 RGD
involved in establishment of protein localization to mitochondrial membrane IMP
IMP: 通过突变表型推断
23792689 RGD
involved in positive regulation of nitric-oxide synthase activity IDA
IDA: 通过直接分析推断
20529840 RGD
involved in regulation of high voltage-gated calcium channel activity IMP
IMP: 通过突变表型推断
18322004 RGD
involved in regulation of ryanodine-sensitive calcium-release channel activity IDA
IDA: 通过直接分析推断
15628869 RGD
involved in regulation of synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
23792689 RGD
involved in regulation of synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
23792689 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
10854758 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
22848456 RGD
located in growth cone IDA
IDA: 通过直接分析推断
7492944 RGD
located in mitochondrial membrane IMP
IMP: 通过突变表型推断
23792689 RGD
located in myelin sheath IDA
IDA: 通过直接分析推断
19855925 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
22848456 RGD
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
22848456 RGD
located in synaptic vesicle membrane IMP
IMP: 通过突变表型推断
23792689 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calmodulin-1

Calmodulin 1 (phosphorylase kinase, delta)

caM

calmodulin I

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01840 CALM1 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calm1 NCBI NCBI:801
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