2. Gene
  3. Cebpa - CCAAT/enhancer binding protein alpha Gene

Cebpa - CCAAT/enhancer binding protein alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: DBPCEP

基因 ID: 24252 | 基因类型: protein coding

关于 Cebpa

功能概要

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. The use of alternative in-frame non-AUG (CUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the CUG and the first AUG start codons. [provided by RefSeq, Aug 2014]

Cebpa 基因产物(4)

mRNA Protein Name
NM_001287577.1 NP_001274506.1 CCAAT/enhancer-binding protein alpha isoform c
NM_001287578.1 NP_001274507.1 CCAAT/enhancer-binding protein alpha isoform d
NM_001287579.1 NP_001274508.1 CCAAT/enhancer-binding protein alpha isoform b
NM_012524.3 NP_036656.1 CCAAT/enhancer-binding protein alpha isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
1377818 RGD
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
8572170 RGD
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
20176812 RGD
enables HMG box domain binding IPI
IPI: 通过物理相互作用推断
16582099 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8572170 RGD
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
23639777 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
1377818 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11356826 RGD
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
8367486 RGD
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
2171780 RGD
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
8367486 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
16172914 RGD
contributes to sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8657121 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
20176812 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
16172914 RGD
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
17047332 RGD
involved in cell differentiation IEP
IEP: 通过表达模式推断
16735515 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
1377818 RGD
involved in fat cell differentiation IDA
IDA: 通过直接分析推断
11672531 RGD
involved in liver development IEP
IEP: 通过表达模式推断
16172914 RGD
involved in memory IEP
IEP: 通过表达模式推断
17512093 RGD
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11672531 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11672531 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8657121 RGD
involved in osteoblast development IEP
IEP: 通过表达模式推断
1377818 RGD
involved in positive regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
11731483 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8572170 RGD
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12554749 RGD
involved in response to dexamethasone IEP
IEP: 通过表达模式推断
12753899 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
16856317 RGD
involved in response to phenylpropanoid IEP
IEP: 通过表达模式推断
23238999 RGD
involved in response to vitamin B2 IEP
IEP: 通过表达模式推断
16856317 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CHOP-C/EBP complex IPI
IPI: 通过物理相互作用推断
8657121 RGD
part of Rb-E2F complex IDA
IDA: 通过直接分析推断
16172914 RGD
located in nuclear matrix IDA
IDA: 通过直接分析推断
16172914 RGD
located in nucleolus IDA
IDA: 通过直接分析推断
20075868 RGD
located in nucleus IDA
IDA: 通过直接分析推断
8657121 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11356826 RGD
part of transcription regulator complex IDA
IDA: 通过直接分析推断
12554749 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CCAAT/enhancer-binding protein alpha

C/EBP alpha

CAAT/enhancer-binding protein, DNA-binding protein

CCAAT/enhancer binding protein (C/EBP), alpha

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-132607A MTL-CEBPA sodium 94.63% Phase 2
HY-132607 MTL-CEBPA 95.52% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168483 FTO-IN-13 / 否
HY-RS02445 CEBPA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18653 Cebpa Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25139 Cebpa Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cebpa NCBI NCBI:1050
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