2. Gene
  3. Cebpb - CCAAT/enhancer binding protein beta Gene

Cebpb - CCAAT/enhancer binding protein beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: TCF5; Il6dbp; NF-IL6

基因 ID: 24253 | 基因类型: protein coding

关于 Cebpb

功能概要

This intronless gene encodes a member of the transcription factor family whose members contain a basic leucine-zipper domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. The encoded protein plays important roles in several cellular processes and in various diseases, including regulating cell proliferation, differentiation, Apoptosis and neuroinflammation, and being involved in brain injury and inflammatory progression. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with different cellular localizations and distinct biological functions. [provided by RefSeq, Sep 2014]

Cebpb 基因产物(3)

mRNA Protein Name
NM_001301715.1 NP_001288644.1 CCAAT/enhancer-binding protein beta isoform LAP2
NM_001301720.1 NP_001288649.1 CCAAT/enhancer-binding protein beta isoform LIP
NM_024125.5 NP_077039.3 CCAAT/enhancer-binding protein beta isoform LAP1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
1377818 RGD
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
8572170 RGD
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
15661831 RGD
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15308669 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8572170 RGD
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
1547942 RGD
enables nuclear glucocorticoid receptor binding IPI
IPI: 通过物理相互作用推断
20155810 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
1377818 RGD
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
1547942 RGD
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
2171780 RGD
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
8367486 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
14661739 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-1 IDA
IDA: 通过直接分析推断
18405661 RGD
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
18405661 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
21877759 RGD
involved in hepatocyte proliferation IDA
IDA: 通过直接分析推断
10635333 RGD
involved in liver development IEP
IEP: 通过表达模式推断
1377818 RGD
involved in memory IEP
IEP: 通过表达模式推断
17512093 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15308669 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
16445384 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8572170 RGD
involved in regulation of odontoblast differentiation IDA
IDA: 通过直接分析推断
15308669 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CHOP-C/EBP complex IPI
IPI: 通过物理相互作用推断
1547942 RGD
located in nuclear matrix IDA
IDA: 通过直接分析推断
12095231 RGD
located in nucleus IDA
IDA: 通过直接分析推断
8657121 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CCAAT/enhancer-binding protein beta

C/EBP beta

CCAAT/enhancer binding protein (C/EBP), beta

IL-6DBP

SF-B

interleukin-6-dependent-binding protein

nuclear factor-IL6

silencer factor B

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02446 CEBPB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17419 Cebpb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23873 Cebpb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cebpb NCBI NCBI:1051
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