2. Gene
  3. Epor - erythropoietin receptor Gene

Epor - erythropoietin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24336 | 基因类型: protein coding

关于 Epor

功能概要

Enables erythropoietin receptor activity. Involved in several processes, including cellular response to kainic acid; negative regulation of cell death; and negative regulation of nitric oxide biosynthetic process. Located in cytoplasm and external side of plasma membrane. Used to study high grade glioma. Biomarker of several diseases, including brain ischemia; cholangiocarcinoma; end stage renal disease; eye disease (multiple); and hepatic encephalopathy. Human ortholog(s) of this gene implicated in anemia; familial erythrocytosis 1; high grade glioma; polycythemia; and systemic lupus erythematosus. Orthologous to human EPOR (erythropoietin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Epor 基因产物(1)

mRNA Protein Name
NM_017002.2 NP_058698.2 erythropoietin receptor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables erythropoietin receptor activity IDA
IDA: 通过直接分析推断
7684373 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to kainic acid IEP
IEP: 通过表达模式推断
18711747 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
12451129 RGD
involved in negative regulation of nitric oxide biosynthetic process IMP
IMP: 通过突变表型推断
10489101 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
21749867 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
21749867 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
7684373 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
22469063 RGD
involved in positive regulation of response to reactive oxygen species IMP
IMP: 通过突变表型推断
23636173 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
21624288 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
27587253 RGD
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
21649646 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

erythropoietin receptor

EPO-R

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-18960 CHZ868 Inhibitor 98.69% 否
HY-W062700 STS-E412 Activator 99.72% 否
HY-RS04448 EPOR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18356 Epor Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24835 Epor Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epor NCBI NCBI:2057
Macaca fascicularis Epor NCBI NCBI:102138718
Mus musculus Epor NCBI NCBI:13857
Macaca mulatta Epor NCBI NCBI:714546
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