1. Gene
  2. Fgg - fibrinogen gamma chain Gene

Fgg - fibrinogen gamma chain Gene

种属: Rattus norvegicus

基因 ID: 24367 | 基因类型: protein coding

关于 Fgg

功能概要

Enables identical protein binding activity. Involved in cellular response to cytokine stimulus; negative regulation of platelet aggregation; and platelet maturation. Located in blood microparticle and cytoplasm. Biomarker of obesity; pancreatitis; and pulmonary embolism. Human ortholog(s) of this gene implicated in brain small vessel disease; congenital afibrinogenemia; and multiple myeloma. Orthologous to human FGG (fibrinogen gamma chain). [provided by Alliance of Genome Resources, Apr 2022]

Fgg 基因产物(1)

mRNA Protein Name
NM_012559.2 NP_036691.2 fibrinogen gamma chain precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
21448983 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
11071643 RGD
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
11071643 RGD
involved in platelet maturation IEP
IEP: 通过表达模式推断
1991167 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in blood microparticle IDA
IDA: 通过直接分析推断
22014850 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fibrinogen gamma chain

fibrinogen, gamma polypeptide

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fgg NCBI NCBI:2266
Mus musculus Fgg NCBI NCBI:99571