2. Gene
  3. Hmgcs2 - 3-hydroxy-3-methylglutaryl-CoA synthase 2 Gene

Hmgcs2 - 3-hydroxy-3-methylglutaryl-CoA synthase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Hmgcs1; Mt3h3mg

基因 ID: 24450 | 基因类型: protein coding

关于 Hmgcs2

功能概要

Enables hydroxymethylglutaryl-CoA synthase activity. Involved in several processes, including animal organ development; cellular response to lipid; and response to peptide hormone. Located in mitochondrial matrix. Biomarker of extrahepatic cholestasis. Orthologous to human HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hmgcs2 基因产物(1)

mRNA Protein Name
NM_173094.2 NP_775117.2 hydroxymethylglutaryl-CoA synthase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hydroxymethylglutaryl-CoA synthase activity IDA
IDA: 通过直接分析推断
1971108 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adipose tissue development IEP
IEP: 通过表达模式推断
10357839 RGD
involved in cellular response to amino acid stimulus IEP
IEP: 通过表达模式推断
20508999 RGD
involved in cellular response to fatty acid IEP
IEP: 通过表达模式推断
20508999 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
9798904 RGD
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
9025717 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
12027802 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
11578593 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
7694571 RGD
involved in ketone body biosynthetic process IEP
IEP: 通过表达模式推断
12399220 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
8099282 RGD
involved in liver development IEP
IEP: 通过表达模式推断
8620869 RGD
involved in lung development IEP
IEP: 通过表达模式推断
7911291 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
8620869 RGD
involved in multicellular organismal response to stress IEP
IEP: 通过表达模式推断
16962226 RGD
involved in response to bacterium IEP
IEP: 通过表达模式推断
14686922 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
7902069 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
17964421 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
10796071 RGD
involved in response to glucagon IEP
IEP: 通过表达模式推断
1967579 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
9546617 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
11551854 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
9143333 RGD
involved in response to linoleic acid IEP
IEP: 通过表达模式推断
16216487 RGD
involved in response to metal ion IEP
IEP: 通过表达模式推断
8100835 RGD
involved in response to monosaccharide IEP
IEP: 通过表达模式推断
1967579 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
17103110 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
20137896 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
12027802 RGD
involved in response to prostaglandin F IEP
IEP: 通过表达模式推断
11517196 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
10357839 RGD
involved in response to temperature stimulus IEP
IEP: 通过表达模式推断
10357839 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
10357839 RGD
involved in response to triglyceride IEP
IEP: 通过表达模式推断
11551854 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11323196 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
17971398 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hydroxymethylglutaryl-CoA synthase, mitochondrial

3-hydroxy-3-methylglutary-Coenzyme A synthase 2

3-hydroxy-3-methylglutaryl coenzyme A synthase

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)

HMG-CoA synthase

hydroxymethylgl

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06242 HMGCS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18424 Hmgcs2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24905 Hmgcs2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hmgcs2 NCBI NCBI:3158
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