1. Gene
  2. Iapp - islet amyloid polypeptide Gene

Iapp - islet amyloid polypeptide Gene

种属: Rattus norvegicus

基因 ID: 24476 | 基因类型: protein coding

关于 Iapp

功能概要

Predicted to enable identical protein binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; Amylin Receptor signaling pathway; and eating behavior. Predicted to be located in inclusion body and neuronal cell body. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human IAPP (islet amyloid polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Iapp 基因产物(1)

mRNA Protein Name
NM_012586.3 NP_036718.1 islet amyloid polypeptide preproprotein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
22500019 RGD
involved in amylin receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
22500019 RGD
involved in eating behavior IMP
IMP: 通过突变表型推断
15130879 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

islet amyloid polypeptide

DAP

amylin

diabetes-associated peptide

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Iapp NCBI NCBI:3375