1. Gene
  2. Nlgn3 - neuroligin 3 Gene

Nlgn3 - neuroligin 3 Gene

种属: Mus musculus

同用名: NL3; HNL3; NLG3; A230085M13Rik

基因 ID: 245537 | 基因类型: protein coding

关于 Nlgn3

功能概要

Predicted to enable several functions, including cell adhesion molecule binding activity; neurexin family protein binding activity; and scaffold protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of neurotransmitter receptor activity; and regulation of synapse organization. Acts upstream of or within several processes, including oligodendrocyte differentiation; regulation of respiratory gaseous exchange by nervous system process; and visual learning. Predicted to be located in endocytic vesicle; excitatory synapse; and neuronal cell body. Predicted to be integral component of postsynaptic membrane. Predicted to be active in cell surface and synapse. Predicted to be integral component of postsynaptic specialization membrane. Predicted to colocalize with dendrite and inhibitory synapse. Is expressed in several structures, including central nervous system; eye; and heart. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in Asperger syndrome and autistic disorder. Orthologous to human NLGN3 (neuroligin 3). [provided by Alliance of Genome Resources, Apr 2022]

Nlgn3 基因产物(1)

mRNA Protein Name
NM_172932.4 NP_766520.2 neuroligin-3 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
21808020 MGI
acts upstream of or within inhibitory postsynaptic potential IMP
IMP: 通过突变表型推断
17823315 MGI
involved in inhibitory postsynaptic potential IMP
IMP: 通过突变表型推断
21808020 MGI
involved in long-term synaptic potentiation IMP
IMP: 通过突变表型推断
21808020 MGI
acts upstream of or within modulation of chemical synaptic transmission IGI
IGI: 通过遗传相互作用推断
16982420 MGI
involved in negative regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
21808020 MGI
involved in negative regulation of excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
21808020 MGI
acts upstream of or within oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
19139271 MGI
involved in positive regulation of AMPA receptor activity IMP
IMP: 通过突变表型推断
21642956 MGI
involved in positive regulation of excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
21642956 MGI
involved in positive regulation of glutamate receptor signaling pathway IMP
IMP: 通过突变表型推断
21642956 MGI
involved in positive regulation of synapse assembly IMP
IMP: 通过突变表型推断
21642956 MGI
involved in positive regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
21642956 MGI
involved in positive regulation of synaptic vesicle clustering IMP
IMP: 通过突变表型推断
21808020 MGI
involved in postsynaptic membrane assembly IMP
IMP: 通过突变表型推断
21642956 MGI
involved in regulation of AMPA receptor activity IMP
IMP: 通过突变表型推断
21808020 MGI
involved in regulation of NMDA receptor activity IMP
IMP: 通过突变表型推断
21808020 MGI
involved in regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
21808020 MGI
involved in regulation of long-term synaptic potentiation IMP
IMP: 通过突变表型推断
21808020 MGI
acts upstream of or within regulation of respiratory gaseous exchange by nervous system process IGI
IGI: 通过遗传相互作用推断
16982420 MGI
involved in regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
21808020 MGI
involved in regulation of terminal button organization IMP
IMP: 通过突变表型推断
21808020 MGI
acts upstream of or within social behavior IMP
IMP: 通过突变表型推断
17823315 MGI
involved in social behavior IMP
IMP: 通过突变表型推断
21808020 MGI
acts upstream of or within synapse organization IGI
IGI: 通过遗传相互作用推断
21788371 MGI
acts upstream of or within visual learning IMP
IMP: 通过突变表型推断
17823315 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neuroligin-3

gliotactin homolog

neuroligin 3 protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nlgn3 NCBI NCBI:54413