2. Gene
  3. SPDYA - speedy/RINGO cell cycle regulator family member A Gene

SPDYA - speedy/RINGO cell cycle regulator family member A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：speedy/RINGO 细胞周期调节因子家族成员 A

种属: Homo sapiens

同用名: SPY1; SPDY1; RINGO3; RINGOA

基因 ID: 245711 | 基因类型: protein coding

关于 SPDYA

Cytogenetic location: 2p23.2 Genomic coordinates (GRCh38): 2:28,810,834-28,850,610 (from NCBI)

This gene has 7 transcripts (splice variants), 188 orthologues and 1 paralogue. Biased expression in testis (RPKM 22.5), duodenum (RPKM 1.7) and 10 other tissues.

功能概要

启用蛋白激酶激活剂活性和蛋白激酶结合活性。参与多个过程，包括有丝分裂细胞周期的 G1/S 转换；细胞群增殖的正向调节；蛋白激酶活性的正调节。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase activator activity and protein kinase binding activity. Involved in several processes, including G1/S transition of mitotic cell cycle; positive regulation of cell population proliferation; and positive regulation of protein kinase activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SPDYA 基因产物(3)

mRNA Protein Name
NM_001008779.1 NP_001008779.1 speedy protein A isoform 2
NM_001142634.2 NP_001136106.1 speedy protein A isoform 1
NM_182756.4 NP_877433.2 speedy protein A isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein kinase activator activity IDA
IDA: 通过直接分析推断
28666995 GOA
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
11980914 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
12839962 GOA
involved in G1/S transition of mitotic cell cycle IDA
IDA: 通过直接分析推断
11980914 GOA
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11980914 GOA
involved in positive regulation of protein kinase activity IDA
IDA: 通过直接分析推断
28666995 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
11980914 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SPDYA 蛋白结构

Spy1

Spy1: Cell cycle regulatory protein (69 - 199)

  • 0
  • 100
  • 200
  • 313 a.a.
蛋白主名 其他名称

speedy protein A

RINGO A

关联疾病

疾病名称 别名
Hypertrophy Of Breast

Breasts Enlarged

Large Breast

Hypertrophy Of Breast Nos

Hypertrophy Of Male Breast

Hypertrophic Breast

Excessive Development Of Breast

Macromastia

Mastoplastia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13654 SPDYA Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SPDYA VGNC VGNC:46728
Mus musculus SPDYA MGD MGI:1918141
Bos taurus SPDYA VGNC VGNC:54492
Macaca mulatta SPDYA VGNC VGNC:106224
Felis catus SPDYA VGNC VGNC:65629
Rattus norvegicus SPDYA RGD RGD:621730
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