1. Gene
  2. FLG - Flg filaggrin Gene

FLG - Flg filaggrin Gene

种属: Rattus norvegicus

同用名: Pflg

基因 ID: 24641 | 基因类型: protein coding

关于 FLG

功能概要

Predicted to enable keratin filament binding activity. Predicted to be a structural constituent of skin epidermis. Involved in epidermal cell differentiation. Predicted to be located in cornified envelope; cytoplasmic ribonucleoprotein granule; and keratohyalin granule. Human ortholog(s) of this gene implicated in atopic dermatitis 2 and ichthyosis vulgaris. Orthologous to human FLG (filaggrin). [provided by Alliance of Genome Resources, Apr 2022]

FLG 基因产物(1)

mRNA Protein Name
NM_001393766.1 NP_001380695.1 filaggrin
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epidermal cell differentiation IMP
IMP: 通过突变表型推断
7688400 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

filaggrin

Filaggrin (profilaggrin)

profilaggrin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens FLG NCBI NCBI:2312