2. Gene
  3. Prlr - prolactin receptor Gene

Prlr - prolactin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RATPRLR

基因 ID: 24684 | 基因类型: protein coding

关于 Prlr

功能概要

Enables Prolactin receptor activity and protein kinase binding activity. Predicted to be involved in several processes, including activation of protein kinase activity; cytokine-mediated signaling pathway; and positive regulation of cold-induced thermogenesis. Predicted to act upstream of or within several processes, including gland development; receptor signaling pathway via JAK-STAT; and response to bacterium. Predicted to be located in cell surface. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in hyperprolactinemia. Orthologous to human PRLR (Prolactin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Prlr 基因产物(2)

mRNA Protein Name
NM_001034111.1 NP_001029283.1 prolactin receptor isoform a precursor
NM_012630.2 NP_036762.1 prolactin receptor isoform b precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prolactin receptor activity IMP
IMP: 通过突变表型推断
11835322 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
7935483 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to granulocyte macrophage colony-stimulating factor stimulus IMP
IMP: 通过突变表型推断
8650199 RGD
involved in positive regulation of B cell proliferation IMP
IMP: 通过突变表型推断
8650199 RGD
involved in positive regulation of protein autophosphorylation IMP
IMP: 通过突变表型推断
8650199 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolactin receptor

PRL-R

lactogen receptor

重组 Prlr 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73693 Prolactin R Protein, Rat (HEK293, His) P05710 (Q20-D229) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11163 PRLR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-NP198 Human prolactin / 否
HY-RS11411 PTP4A3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17413 Prlr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23867 Prlr Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99238 Rolinsatamab 97.16% 否
HY-P991358 XOMA-213 Inhibitor / 否
HY-P99881 Rolinsatamab talirine / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prlr NCBI NCBI:5618
Mus musculus Prlr NCBI NCBI:19116
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