2. Gene
  3. Ptgs1 - prostaglandin-endoperoxide synthase 1 Gene

Ptgs1 - prostaglandin-endoperoxide synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cox1; Cox3; Cox-1; Cox-3; Pghs-1

基因 ID: 24693 | 基因类型: protein coding

关于 Ptgs1

功能概要

This is one of two genes encoding similar Enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. [provided by RefSeq, Jan 2014]

Ptgs1 基因产物(1)

mRNA Protein Name
NM_017043.4 NP_058739.4 prostaglandin G/H synthase 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in learning IMP
IMP: 通过突变表型推断
21701788 RGD
involved in maintenance of blood-brain barrier IMP
IMP: 通过突变表型推断
17704356 RGD
involved in memory IMP
IMP: 通过突变表型推断
21701788 RGD
involved in negative regulation of epinephrine secretion IMP
IMP: 通过突变表型推断
18598693 RGD
involved in negative regulation of norepinephrine secretion IMP
IMP: 通过突变表型推断
18598693 RGD
involved in positive regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
18480553 RGD
involved in positive regulation of vasoconstriction IMP
IMP: 通过突变表型推断
17245358 RGD
involved in prostaglandin biosynthetic process IMP
IMP: 通过突变表型推断
17673564 RGD
involved in response to corticosterone IEP
IEP: 通过表达模式推断
18584335 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
16983392 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear envelope IDA
IDA: 通过直接分析推断
12657565 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prostaglandin G/H synthase 1

PGH synthase 1

PHS 1

cyclooxygenase 3

cyclooxygenase-1

prostaglandin G/H synthase and cyclooxygenase

prostaglandin H2 synthase 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11392 PTGS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19231 Ptgs1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25720 Ptgs1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgs1 NCBI NCBI:5742
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