1. Gene
  2. Slc4a1 - solute carrier family 4 member 1 (Diego blood group) Gene

Slc4a1 - solute carrier family 4 member 1 (Diego blood group) Gene

种属: Rattus norvegicus

基因 ID: 24779 | 基因类型: protein coding

关于 Slc4a1

功能概要

Enables actin binding activity; enzyme binding activity; and protein C-terminus binding activity. Involved in several processes, including positive regulation of T cell proliferation; response to alkaline pH; and response to carbon dioxide. Located in several cellular components, including Z disc; basolateral plasma membrane; and intercalated disc. Biomarker of iron deficiency anemia; metabolic acidosis; and renal tubular acidosis. Human ortholog(s) of this gene implicated in congenital hemolytic anemia; hereditary spherocytosis; hereditary spherocytosis type 4; malaria; and renal tubular acidosis. Orthologous to human SLC4A1 (solute carrier family 4 member 1 (Diego blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Slc4a1 基因产物(1)

mRNA Protein Name
NM_012651.2 NP_036783.2 band 3 anion transport protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IPI
IPI: 通过物理相互作用推断
12898519 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
17652430 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
20946910 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IEP
IEP: 通过表达模式推断
21903759 RGD
involved in positive regulation of T cell proliferation IDA
IDA: 通过直接分析推断
12165075 RGD
involved in response to acidic pH IEP
IEP: 通过表达模式推断
10600930 RGD
involved in response to activity IDA
IDA: 通过直接分析推断
24289085 RGD
involved in response to alkaline pH IEP
IEP: 通过表达模式推断
10600930 RGD
involved in response to arsenic-containing substance IDA
IDA: 通过直接分析推断
20946910 RGD
involved in response to carbon dioxide IDA
IDA: 通过直接分析推断
15075205 RGD
involved in response to hydrogen peroxide IDA
IDA: 通过直接分析推断
20946910 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
21903759 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
12898519 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
9596071 RGD
located in cell surface IDA
IDA: 通过直接分析推断
20114059 RGD
located in intercalated disc IDA
IDA: 通过直接分析推断
12898519 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

band 3 anion transport protein

AE 1

Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3)

anion exchange protein 1

anion exchanger 1

solute carrier family 4 (anion exchanger), member 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc4a1 NCBI NCBI:6521