1. Gene
  2. Tac1 - tachykinin, precursor 1 Gene

Tac1 - tachykinin, precursor 1 Gene

种属: Rattus norvegicus

同用名: TAC; PPTA3; Ppt5fl; RATPPTA3

基因 ID: 24806 | 基因类型: protein coding

关于 Tac1

功能概要

Enables substance P receptor binding activity. Involved in several processes, including learning or memory; positive regulation of secretion; and positive regulation of synaptic transmission. Located in extracellular space and plasma membrane. Used to study central sleep apnea and pulmonary hypertension. Biomarker of colitis and respiratory syncytial virus infectious disease. Orthologous to human TAC1 (tachykinin precursor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tac1 基因产物(4)

mRNA Protein Name
NM_001124768.1 NP_001118240.1 protachykinin-1 isoform b precursor
NM_001124769.1 NP_001118241.1 protachykinin-1 isoform c precursor
NM_001124770.1 NP_001118242.1 protachykinin-1 isoform d precursor
NM_012666.2 NP_036798.1 protachykinin-1 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables substance P receptor binding IDA
IDA: 通过直接分析推断
18634782 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in associative learning IDA
IDA: 通过直接分析推断
19071162 RGD
involved in long-term memory IDA
IDA: 通过直接分析推断
19071162 RGD
involved in negative regulation of heart rate IDA
IDA: 通过直接分析推断
2471579 RGD
involved in positive regulation of action potential IDA
IDA: 通过直接分析推断
18158108 RGD
involved in positive regulation of acute inflammatory response IDA
IDA: 通过直接分析推断
19222484 RGD
involved in positive regulation of corticosterone secretion IDA
IDA: 通过直接分析推断
8391371 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
18634782 RGD
involved in positive regulation of epithelial cell migration IDA
IDA: 通过直接分析推断
17435548 RGD
involved in positive regulation of lymphocyte proliferation IMP
IMP: 通过突变表型推断
18621988 RGD
involved in positive regulation of ossification IDA
IDA: 通过直接分析推断
17204323 RGD
involved in positive regulation of stress fiber assembly IDA
IDA: 通过直接分析推断
17435548 RGD
involved in positive regulation of synaptic transmission, GABAergic IDA
IDA: 通过直接分析推断
19261870 RGD
involved in positive regulation of synaptic transmission, cholinergic IDA
IDA: 通过直接分析推断
17949415 RGD
involved in regulation of blood pressure IDA
IDA: 通过直接分析推断
18938661 RGD
involved in response to hormone IMP
IMP: 通过突变表型推断
18195491 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18337316 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18337316 RGD
is active in neuronal dense core vesicle IDA
IDA: 通过直接分析推断
6167867 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protachykinin-1

PPT

Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma)

tachykinin 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tac1 NCBI NCBI:6863