2. Gene
  3. Tpm1 - tropomyosin 1 Gene

Tpm1 - tropomyosin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Tma2; Tmsa; Alpha-tm

基因 ID: 24851 | 基因类型: protein coding

关于 Tpm1

功能概要

This gene is a member of the tropomyosin family and encodes a protein that heterodimerizes with a beta subunit, binding actin in both muscle and nonmuscle cells. In both smooth and striated muscle cells, it plays a role in calcium dependent-regulation of muscle contraction. In nonmuscle cells, it stabilizes Cytoskeleton actin filaments. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Tpm1 基因产物(12)

mRNA Protein Name
NM_001034068.1 NP_001029240.1 tropomyosin alpha-1 chain isoform a
NM_001034069.1 NP_001029241.1 tropomyosin alpha-1 chain isoform Tpm1.6cy
NM_001034070.1 NP_001029242.1 tropomyosin alpha-1 chain isoform Tpm1.7cy
NM_001034071.1 NP_001029243.1 tropomyosin alpha-1 chain isoform Tpm1.3sm
NM_001034072.1 NP_001029244.1 tropomyosin alpha-1 chain isoform Tpm1.10br
NM_001034073.1 NP_001029245.1 tropomyosin alpha-1 chain isoform Tpm1.8cy
NM_001034074.1 NP_001029246.1 tropomyosin alpha-1 chain isoform Tpm1.9cy
NM_001034075.1 NP_001029247.1 tropomyosin alpha-1 chain isoform Tpm1.13
NM_001301336.1 NP_001288265.1 tropomyosin alpha-1 chain isoform Tpm1.1st
NM_001301342.1 NP_001288271.1 tropomyosin alpha-1 chain isoform Tpm1.2st
NM_001301736.1 NP_001288665.1 tropomyosin alpha-1 chain isoform Tpm1.12br
NM_019131.2 NP_062004.1 tropomyosin alpha-1 chain isoform Tpm1.11br
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
19041430 RGD
enables actin binding IMP
IMP: 通过突变表型推断
14640678 RGD
enables actin filament binding IDA
IDA: 通过直接分析推断
7568216 RGD
enables actin filament binding IMP
IMP: 通过突变表型推断
11329279 RGD
enables disordered domain specific binding IPI
IPI: 通过物理相互作用推断
15475586 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
7568216 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16420482 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15779917 RGD
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
7568216 RGD
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
7568216 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament capping IDA
IDA: 通过直接分析推断
15779917 RGD
involved in cardiac muscle contraction IDA
IDA: 通过直接分析推断
14551059 RGD
involved in muscle filament sliding IDA
IDA: 通过直接分析推断
11136687 RGD
involved in negative regulation of cell migration IGI
IGI: 通过遗传相互作用推断
15897890 RGD
involved in positive regulation of ATP-dependent activity IDA
IDA: 通过直接分析推断
11136687 RGD
involved in positive regulation of ATP-dependent activity IMP
IMP: 通过突变表型推断
11329279 RGD
involved in positive regulation of cell adhesion IGI
IGI: 通过遗传相互作用推断
17721995 RGD
involved in positive regulation of stress fiber assembly IGI
IGI: 通过遗传相互作用推断
15897890 RGD
involved in regulation of ATP-dependent activity IDA
IDA: 通过直接分析推断
19041430 RGD
involved in ruffle organization IGI
IGI: 通过遗传相互作用推断
15897890 RGD
involved in wound healing IGI
IGI: 通过遗传相互作用推断
17721995 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
7568216 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15823548 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tropomyosin alpha-1 chain

hepatoma alpha tropomyosin

smooth muscle alpha-tropomyosin

striated muscle alpha-tropomyosin

tropomyosin 1, alpha

tropomyosin 3 alpha

tropomyosin-alpha

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14936 TPM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17596 Tpm1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24056 Tpm1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpm1 NCBI NCBI:7168
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z