1. Gene
  2. Clu - clusterin Gene

Clu - clusterin Gene

种属: Rattus norvegicus

同用名: CLI; DAG; APOJ; SGP2; SP40; SGP-2; SP-40; Trpm2; Trpmb; TRPM-2; TRPM2B; RATTRPM2B

基因 ID: 24854 | 基因类型: protein coding

关于 Clu

功能概要

The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders.[provided by RefSeq, May 2011]

Clu 基因产物(1)

mRNA Protein Name
NM_053021.3 NP_444180.3 clusterin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11570883 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to growth factor stimulus IEP
IEP: 通过表达模式推断
16038898 RGD
involved in endocrine pancreas development IMP
IMP: 通过突变表型推断
16411126 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
11149574 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
15591223 RGD
involved in negative regulation of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
23164821 RGD
involved in neuron projection morphogenesis IMP
IMP: 通过突变表型推断
16038898 RGD
involved in positive regulation of cell differentiation IMP
IMP: 通过突变表型推断
16411126 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15591223 RGD
involved in positive regulation of gene expression IGI
IGI: 通过遗传相互作用推断
23164821 RGD
involved in protein stabilization IDA
IDA: 通过直接分析推断
11570883 RGD
involved in response to light stimulus IEP
IEP: 通过表达模式推断
11803476 RGD
involved in response to potassium ion IEP
IEP: 通过表达模式推断
12782389 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in aggresome IDA
IDA: 通过直接分析推断
12799419 RGD
located in cytosol IDA
IDA: 通过直接分析推断
16038898 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
11570883 RGD
located in growth cone IDA
IDA: 通过直接分析推断
16038898 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
16038898 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

clusterin

dimeric acid glycoprotein

sulfated glycoprotein 2

testosterone repressed prostate message 2

testosterone-repressed prostate message

testostrone-repressed prostate message 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Clu NCBI NCBI:1191
Mus musculus Clu NCBI NCBI:12759