2. Gene
  3. Ptger3 - prostaglandin E receptor 3 Gene

Ptger3 - prostaglandin E receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: EP3; EP3R; Rep3; rEP3a; rEP3b

基因 ID: 24929 | 基因类型: protein coding

关于 Ptger3

功能概要

Enables prostaglandin E receptor activity. Involved in several processes, including negative regulation of G protein-coupled receptor signaling pathway; negative regulation of transport; and positive regulation of smooth muscle contraction. Located in several cellular components, including brush border membrane; nuclear membrane; and proximal neuron projection. Used to study asthma and withdrawal disorder. Biomarker of colon cancer; membranous glomerulonephritis; and renovascular hypertension. Orthologous to human PTGER3 (prostaglandin E receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ptger3 基因产物(1)

mRNA Protein Name
NM_012704.1 NP_036836.1 prostaglandin E2 receptor EP3 subtype
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prostaglandin E receptor activity IDA
IDA: 通过直接分析推断
10336471 RGD
enables prostaglandin E receptor activity IMP
IMP: 通过突变表型推断
9350980 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cAMP biosynthetic process IMP
IMP: 通过突变表型推断
11278900 RGD
involved in cAMP/PKA signal transduction IMP
IMP: 通过突变表型推断
11278900 RGD
involved in cellular response to forskolin IMP
IMP: 通过突变表型推断
15937517 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
16405508 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
14636300 RGD
involved in cellular response to prostaglandin E stimulus IMP
IMP: 通过突变表型推断
11278900 RGD
involved in desensitization of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
9350980 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
10819751 RGD
involved in intestine smooth muscle contraction IMP
IMP: 通过突变表型推断
24170253 RGD
involved in maternal process involved in parturition IEP
IEP: 通过表达模式推断
19801535 RGD
involved in negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
9013884 RGD
involved in negative regulation of calcium ion transmembrane transport IMP
IMP: 通过突变表型推断
10670413 RGD
involved in negative regulation of circadian sleep/wake cycle, wakefulness IMP
IMP: 通过突变表型推断
10923657 RGD
involved in negative regulation of forebrain neuron differentiation IMP
IMP: 通过突变表型推断
19555672 RGD
involved in negative regulation of gastrin-induced gastric acid secretion IMP
IMP: 通过突变表型推断
15961884 RGD
involved in negative regulation of insulin secretion IDA
IDA: 通过直接分析推断
10531320 RGD
involved in negative regulation of norepinephrine secretion IMP
IMP: 通过突变表型推断
12524145 RGD
involved in negative regulation of potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
18496512 RGD
involved in positive regulation of calcitonin secretion IMP
IMP: 通过突变表型推断
11278900 RGD
involved in positive regulation of circadian sleep/wake cycle, non-REM sleep IMP
IMP: 通过突变表型推断
10923657 RGD
involved in positive regulation of colon smooth muscle contraction IMP
IMP: 通过突变表型推断
24170253 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
8743550 RGD
involved in positive regulation of gastric mucosal blood circulation IMP
IMP: 通过突变表型推断
10807413 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
17408863 RGD
involved in positive regulation of inhibitory G protein-coupled receptor phosphorylation IMP
IMP: 通过突变表型推断
15937517 RGD
involved in positive regulation of myofibroblast contraction IMP
IMP: 通过突变表型推断
19239477 RGD
involved in positive regulation of neutrophil extravasation IMP
IMP: 通过突变表型推断
15944932 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
15937517 RGD
involved in positive regulation of smooth muscle contraction involved in micturition IMP
IMP: 通过突变表型推断
18562635 RGD
involved in positive regulation of substance P secretion IMP
IMP: 通过突变表型推断
11278900 RGD
involved in positive regulation of vasoconstriction IMP
IMP: 通过突变表型推断
10747002 RGD
involved in prostaglandin receptor internalization IMP
IMP: 通过突变表型推断
15937517 RGD
involved in receptor internalization IMP
IMP: 通过突变表型推断
15937517 RGD
involved in regulation of circadian sleep/wake cycle, wakefulness IMP
IMP: 通过突变表型推断
10923657 RGD
involved in regulation of norepinephrine secretion IMP
IMP: 通过突变表型推断
12524145 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
10819751 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
19801535 RGD
involved in response to salt IEP
IEP: 通过表达模式推断
10432392 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19801535 RGD
involved in urinary bladder smooth muscle contraction IMP
IMP: 通过突变表型推断
18562635 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in brush border membrane IDA
IDA: 通过直接分析推断
15292051 RGD
located in cell surface IDA
IDA: 通过直接分析推断
15937517 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
20336467 RGD
located in nuclear membrane IDA
IDA: 通过直接分析推断
10336471 RGD
located in proximal neuron projection IDA
IDA: 通过直接分析推断
21104189 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prostaglandin E2 receptor EP3 subtype

PGE receptor, EP3 subtype

PGE2 receptor EP3 subtype

prostaglandin E receptor 3 (subtype EP3)

prostanoid EP3 receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11377 PTGER3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20586 Ptger3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27094 Ptger3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptger3 NCBI NCBI:5733
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