2. Gene
  3. Calcrl - calcitonin receptor like receptor Gene

Calcrl - calcitonin receptor like receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CLR; Crlr; RNCLR; RATCRLR

基因 ID: 25029 | 基因类型: protein coding

关于 Calcrl

功能概要

Predicted to enable Adrenomedullin binding activity; Adrenomedullin receptor activity; and Calcitonin gene-related peptide receptor activity. Involved in negative regulation of inflammatory response and negative regulation of smooth muscle contraction. Predicted to be located in endoplasmic reticulum; endosome; and lysosome. Predicted to be part of CGRP Receptor complex and Adrenomedullin receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CALCRL (Calcitonin receptor like receptor). [provided by Alliance of Genome Resources, Apr 2022]

Calcrl 基因产物(1)

mRNA Protein Name
NM_012717.3 NP_036849.2 calcitonin gene-related peptide type 1 receptor precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
17363466 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in neuronal dense core vesicle IDA
IDA: 通过直接分析推断
17614212 RGD
is active in synaptic vesicle IDA
IDA: 通过直接分析推断
17614212 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcitonin gene-related peptide type 1 receptor

CGRP type 1 receptor

calcitonin receptor-like

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01835 CALCRL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20140 Calcrl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26644 Calcrl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Calcrl NCBI NCBI:10203
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