2. Gene
  3. Chrna5 - cholinergic receptor nicotinic alpha 5 subunit Gene

Chrna5 - cholinergic receptor nicotinic alpha 5 subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25102 | 基因类型: protein coding

关于 Chrna5

功能概要

Enables acetylcholine binding activity and acetylcholine-gated cation-selective channel activity. Predicted to be involved in several processes, including behavioral response to nicotine; cholinergic synaptic transmission; and regulation of synaptic vesicle exocytosis. Located in dendrite; neuronal cell body; and plasma membrane. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in lung Cancer. Orthologous to human CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna5 基因产物(1)

mRNA Protein Name
NM_017078.2 NP_058774.2 neuronal acetylcholine receptor subunit alpha-5 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables acetylcholine binding IDA
IDA: 通过直接分析推断
11297818 RGD
enables acetylcholine-gated monoatomic cation-selective channel activity IMP
IMP: 通过突变表型推断
11297818 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
20566638 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
20796176 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in behavioral response to nicotine IMP
IMP: 通过突变表型推断
21278726 RGD
involved in cellular response to nicotine IMP
IMP: 通过突变表型推断
30293722 RGD
involved in detection of mechanical stimulus involved in sensory perception of pain IMP
IMP: 通过突变表型推断
15652389 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
15558717 RGD
involved in regulation of neuronal action potential IMP
IMP: 通过突变表型推断
30293722 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of acetylcholine-gated channel complex IDA
IDA: 通过直接分析推断
20796176 RGD
located in dendrite IDA
IDA: 通过直接分析推断
11297818 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
11297818 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuronal acetylcholine receptor subunit alpha-5

acetylcholine receptor alpha 5

cholinergic receptor, nicotinic, alpha 5 (neuronal)

cholinergic receptor, nicotinic, alpha polypeptide 5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS19054 Chrna5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS02670 CHRNA5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25544 Chrna5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrna5 NCBI NCBI:1138
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