2. Gene
  3. Cyp17a1 - cytochrome P450, family 17, subfamily a, polypeptide 1 Gene

Cyp17a1 - cytochrome P450, family 17, subfamily a, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cyp17

基因 ID: 25146 | 基因类型: protein coding

关于 Cyp17a1

功能概要

Enables steroid 17-alpha-monooxygenase activity. Involved in several processes, including animal organ development; response to fungicide; and response to Herbicide. Located in cell projection; endoplasmic reticulum; and neuronal cell body. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; congenital adrenal hyperplasia; gallbladder cancer; osteoporosis; and prostate Cancer. Orthologous to human CYP17A1 (Cytochrome P450 family 17 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp17a1 基因产物(1)

mRNA Protein Name
NM_012753.3 NP_036885.2 steroid 17-alpha-hydroxylase/17,20 lyase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables steroid 17-alpha-monooxygenase activity IDA
IDA: 通过直接分析推断
2786990 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Leydig cell differentiation IEP
IEP: 通过表达模式推断
18502897 RGD
involved in adrenal gland development IEP
IEP: 通过表达模式推断
17065412 RGD
involved in biphenyl metabolic process IEP
IEP: 通过表达模式推断
20356859 RGD
involved in cellular response to antibiotic IEP
IEP: 通过表达模式推断
18655822 RGD
involved in cellular response to gonadotropin stimulus IEP
IEP: 通过表达模式推断
20963569 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
20665543 RGD
involved in dibenzo-p-dioxin metabolic process IEP
IEP: 通过表达模式推断
20059580 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
21047951 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
10822021 RGD
involved in organic acid metabolic process IEP
IEP: 通过表达模式推断
17400581 RGD
involved in phenol-containing compound metabolic process IEP
IEP: 通过表达模式推断
18191889 RGD
involved in phthalate metabolic process IEP
IEP: 通过表达模式推断
16809437 RGD
involved in positive regulation of steroid hormone biosynthetic process IMP
IMP: 通过突变表型推断
19615041 RGD
involved in response to acetate IEP
IEP: 通过表达模式推断
21046364 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
17291543 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
15958400 RGD
involved in response to fungicide IEP
IEP: 通过表达模式推断
16214947 RGD
involved in response to gonadotropin IEP
IEP: 通过表达模式推断
17291543 RGD
involved in response to herbicide IEP
IEP: 通过表达模式推断
20667998 RGD
involved in response to insecticide IEP
IEP: 通过表达模式推断
17569032 RGD
involved in response to ionizing radiation IEP
IEP: 通过表达模式推断
18821396 RGD
involved in response to methylmercury IEP
IEP: 通过表达模式推断
17869401 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
17936465 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18923996 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
19497980 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
19961867 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
17291543 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19603415 RGD
involved in steroid biosynthetic process IMP
IMP: 通过突变表型推断
2786990 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
15934942 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15934942 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

steroid 17-alpha-hydroxylase/17,20 lyase

17-alpha-hydroxyprogesterone aldolase

CYPXVII

Cytochrome P450, subfamily XVII

P450-C17

P45017alpha

P450c17

cytochrome P450 17A1

cytochrome P450, subfamily 17

cytochrome P450-C17

cytochrome P450c17

steroid 17-alpha-monooxygenase

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-163359 CYP17A1/HDAC6-IN-1 Inhibitor / 否
HY-164457 ASN-001 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp17a1 NCBI NCBI:1586
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