1. Gene
  2. Rxra - retinoid X receptor alpha Gene

Rxra - retinoid X receptor alpha Gene

种属: Rattus norvegicus

基因 ID: 25271 | 基因类型: protein coding

关于 Rxra

功能概要

Enables protein domain specific binding activity and retinoic acid receptor binding activity. Contributes to double-stranded DNA binding activity. Involved in several processes, including cellular response to Insulin stimulus; response to retinoic acid; and response to vitamin. Located in axon and nucleus. Biomarker of alcoholic cardiomyopathy and prostate carcinoma in situ. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human RXRA (retinoid X receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Rxra 基因产物(1)

mRNA Protein Name
NM_012805.3 NP_036937.2 retinoic acid receptor RXR-alpha
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to double-stranded DNA binding IDA
IDA: 通过直接分析推断
17483744 RGD
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables nuclear thyroid hormone receptor binding IPI
IPI: 通过物理相互作用推断
10037764 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9199332 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
9742117 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon regeneration IEP
IEP: 通过表达模式推断
16782282 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
9555940 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
16135695 RGD
involved in liver development IEP
IEP: 通过表达模式推断
14729401 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
15964596 RGD
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16344269 RGD
involved in placenta development IEP
IEP: 通过表达模式推断
16135695 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
16344269 RGD
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12105223 RGD
involved in regulation of myelination IDA
IDA: 通过直接分析推断
20648638 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
19791468 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
17483744 RGD
involved in response to glucocorticoid IMP
IMP: 通过突变表型推断
19008781 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
14986719 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17270546 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
9555940 RGD
involved in response to selenium ion IEP
IEP: 通过表达模式推断
15318950 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
16180333 RGD
involved in response to vitamin D IEP
IEP: 通过表达模式推断
12048211 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
16782282 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

retinoic acid receptor RXR-alpha

nuclear receptor subfamily 2 group B member 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rxra NCBI NCBI:6256