2. Gene
  3. Gdf5 - growth differentiation factor 5 Gene

Gdf5 - growth differentiation factor 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cdmp1

基因 ID: 252835 | 基因类型: protein coding

关于 Gdf5

功能概要

Enables signaling receptor binding activity. Involved in several processes, including negative regulation of neuron apoptotic process; ossification involved in bone remodeling; and positive regulation of neuron differentiation. Predicted to be active in extracellular space. Biomarker of Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease and bone disease (multiple). Orthologous to human GDF5 (Growth Differentiation Factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Gdf5 基因产物(1)

mRNA Protein Name
NM_001398661.1 NP_001385590.1 growth differentiation factor 5 preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IMP
IMP: 通过突变表型推断
15906156 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
15906156 RGD
involved in ossification involved in bone remodeling IEP
IEP: 通过表达模式推断
10404008 RGD
involved in positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
15906156 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
10404008 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

growth differentiation factor 5

growth/differentiation factor 5

cartilage-derived morphogenetic protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05355 GDF5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18243 Gdf5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24722 Gdf5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gdf5 NCBI NCBI:8200
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