2. Gene
  3. Usp7 - ubiquitin specific peptidase 7 Gene

Usp7 - ubiquitin specific peptidase 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hausp; 2210010O09Rik

基因 ID: 252870 | 基因类型: protein coding

关于 Usp7

功能概要

Enables cysteine-type endopeptidase activity and thiol-dependent Deubiquitinase. Involved in histone H2B conserved C-terminal lysine deubiquitination; regulation of circadian rhythm; and regulation of protein stability. Located in XY body; cytoplasm; and nucleus. Is expressed in embryo and trophectoderm. Orthologous to human USP7 (ubiquitin specific peptidase 7). [provided by Alliance of Genome Resources, Apr 2022]

Usp7 基因产物(1)

mRNA Protein Name
NM_001003918.2 NP_001003918.2 ubiquitin carboxyl-terminal hydrolase 7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cysteine-type deubiquitinase activity IDA
IDA: 通过直接分析推断
21268065 MGI
enables cysteine-type deubiquitinase activity IMP
IMP: 通过突变表型推断
27863226 MGI
enables cysteine-type endopeptidase activity IMP
IMP: 通过突变表型推断
21268065 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18716620 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein deubiquitination IDA
IDA: 通过直接分析推断
21268065 MGI
involved in regulation of circadian rhythm IMP
IMP: 通过突变表型推断
27123980 MGI
involved in regulation of protein stability IMP
IMP: 通过突变表型推断
27123980 MGI
involved in transcription elongation-coupled chromatin remodeling IMP
IMP: 通过突变表型推断
27863226 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in XY body IDA
IDA: 通过直接分析推断
25634095 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
12093161 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12093161 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase 7

deubiquitinating enzyme 7

herpesvirus-associated ubiquitin-specific protease

mHAUSP

ubiquitin specific protease 7

ubiquitin thioesterase 7

ubiquitin thiolesterase 7

ubiquitin-specific-processing protease 7

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101666 HBX 41108 Inhibitor 98.91% 否
HY-158039 YCH2823 Inhibitor 99.87% 否
HY-148369 U7D-1 Inhibitor 99.68% 否
HY-175360 USP7 Ligand-Linker Conjugates 1 Inhibitor 99.89% 否
HY-168121 USP7-IN-15 Inhibitor / 否
HY-175359 USP7-IN-19 Inhibitor / 否
HY-162794 YCH3124 Inhibitor / 否
HY-159175 XM-U-14 Degrader / 否
HY-153942 USP7-IN-12 Inhibitor / 否
HY-159964 USP7-IN-16 Inhibitor / 否
HY-175358 PROTAC USP7 Degrader-1 Degrader / 否
HY-164544 USP7-055 Inhibitor / 否
HY-124739 HBX 28258 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Usp7 NCBI NCBI:7874
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