2. Gene
  3. Nr1d1 - nuclear receptor subfamily 1, group D, member 1 Gene

Nr1d1 - nuclear receptor subfamily 1, group D, member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: REV-ERBAALPHA

基因 ID: 252917 | 基因类型: protein coding

关于 Nr1d1

功能概要

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor Aryl Hydrocarbon Receptor nuclear translocator-like protein 1 (Arntl). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Feb 2014]

Nr1d1 基因产物(2)

mRNA Protein Name
NM_001113422.2 NP_001106893.2 nuclear receptor subfamily 1 group D member 1 isoform 1
NM_145775.3 NP_665718.2 nuclear receptor subfamily 1 group D member 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21874017 RGD
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
8474464 RGD
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
8015547 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IEP
IEP: 通过表达模式推断
24144766 RGD
involved in photoperiodism IEP
IEP: 通过表达模式推断
21076970 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
22425774 RGD
involved in positive regulation of circadian rhythm IDA
IDA: 通过直接分析推断
18946026 RGD
involved in regulation of circadian rhythm IDA
IDA: 通过直接分析推断
22425774 RGD
involved in regulation of hepatic stellate cell activation IDA
IDA: 通过直接分析推断
24497272 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
21874017 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
21874017 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor subfamily 1 group D member 1

EAR-1

V-erbA-related protein 1

V-erbA-related protein EAR-1

rev-erb alpha

rev-erbA-alpha

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09527 NR1D1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18073 Nr1d1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24548 Nr1d1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nr1d1 NCBI NCBI:9572
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