1. Gene
  2. Fnta - farnesyltransferase, CAAX box, alpha Gene

Fnta - farnesyltransferase, CAAX box, alpha Gene

种属: Rattus norvegicus

同用名: PFAS

基因 ID: 25318 | 基因类型: protein coding

关于 Fnta

功能概要

Contributes to several functions, including peptide binding activity; Protein Prenyltransferase activity; and zinc ion binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cell population proliferation; and regulation of nitric-oxide synthase biosynthetic process. Located in cytoplasm. Part of CAAX-protein geranylgeranyltransferase complex. Orthologous to human FNTA (farnesyltransferase, CAAX box, alpha). [provided by Alliance of Genome Resources, Apr 2022]

Fnta 基因产物(1)

mRNA Protein Name
NM_012847.2 NP_036979.2 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to CAAX-protein geranylgeranyltransferase activity IDA
IDA: 通过直接分析推断
8089111 RGD
contributes to heterocyclic compound binding IDA
IDA: 通过直接分析推断
15248757 RGD
contributes to peptide binding IDA
IDA: 通过直接分析推断
9705207 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9065406 RGD
contributes to protein farnesyltransferase activity IDA
IDA: 通过直接分析推断
8089111 RGD
enables protein farnesyltransferase activity IDA
IDA: 通过直接分析推断
1763049 RGD
contributes to small molecule binding IDA
IDA: 通过直接分析推断
15248757 RGD
contributes to zinc ion binding IDA
IDA: 通过直接分析推断
15248757 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
11313965 RGD
involved in negative regulation of nitric-oxide synthase biosynthetic process IMP
IMP: 通过突变表型推断
9153192 RGD
involved in positive regulation of cell cycle IMP
IMP: 通过突变表型推断
10544242 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
10544242 RGD
involved in positive regulation of nitric-oxide synthase biosynthetic process IMP
IMP: 通过突变表型推断
9153192 RGD
involved in response to cytokine IMP
IMP: 通过突变表型推断
9153192 RGD
involved in response to organic cyclic compound IMP
IMP: 通过突变表型推断
16257390 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CAAX-protein geranylgeranyltransferase complex IDA
IDA: 通过直接分析推断
15248757 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

CAAX farnesyltransferase subunit alpha

FTase-alpha

Farnesyltransferase, subunit alpha

GGTase-I-alpha

ras proteins prenyltransferase subunit alpha

type I protein geranyl-geranyltransferase subunit alpha

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fnta NCBI NCBI:2339