1. Gene
  2. Sftpd - surfactant protein D Gene

Sftpd - surfactant protein D Gene

种属: Rattus norvegicus

同用名: SPD; SP-D

基因 ID: 25350 | 基因类型: protein coding

关于 Sftpd

功能概要

Enables identical protein binding activity; lipopolysaccharide binding activity; and monosaccharide binding activity. Involved in several processes, including negative regulation of interleukin-2 production; opsonization; and regulation of phagocytosis. Located in extracellular space; multivesicular body; and rough endoplasmic reticulum. Biomarker of Coronavirus infectious disease; asthma; Bacterial pneumonia; lung disease; and newborn respiratory distress syndrome. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to human SFTPD (surfactant protein D). [provided by Alliance of Genome Resources, Apr 2022]

Sftpd 基因产物(1)

mRNA Protein Name
NM_012878.3 NP_037010.1 pulmonary surfactant-associated protein D precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
19017984 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
19007302 RGD
enables lipopolysaccharide binding IDA
IDA: 通过直接分析推断
18092821 RGD
enables monosaccharide binding IDA
IDA: 通过直接分析推断
18092821 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of T cell proliferation IDA
IDA: 通过直接分析推断
9794387 RGD
involved in negative regulation of interleukin-2 production IDA
IDA: 通过直接分析推断
9794387 RGD
involved in negative regulation of phagocytosis IDA
IDA: 通过直接分析推断
12654779 RGD
involved in opsonization IDA
IDA: 通过直接分析推断
19017984 RGD
involved in positive regulation of phagocytosis IDA
IDA: 通过直接分析推断
15591410 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
8292379 RGD
involved in response to growth factor IEP
IEP: 通过表达模式推断
11076805 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
11472975 RGD
involved in surfactant homeostasis IDA
IDA: 通过直接分析推断
9201966 RGD
involved in surfactant homeostasis IMP
IMP: 通过突变表型推断
10666121 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
11472975 RGD
located in multivesicular body IDA
IDA: 通过直接分析推断
16187065 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pulmonary surfactant-associated protein D

CP4

PSP-D

lung surfactant protein D

pulmonary surfactant protein D

surfactant associated protein D

surfactant, pulmonary-associated protein D

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sftpd NCBI NCBI:6441
Mus musculus Sftpd NCBI NCBI:20390
Macaca mulatta Sftpd NCBI NCBI:678657